Immunosuppressive Drugs as a Possible Cause of Psychiatric Complications in Patients after Organ Transplantation

Czech version

Authors: A. Procházková; R. Honzák
Authors‘ workplace: Psychiatrická katedra IPVZ, Praha, přednosta prof. MUDr. K. Chromý, CSc.
Published in: Prakt. Lék. 2003; (2): 96-98
Category:

Overview

Immunosuppressive drugs are mandatory in patients after organ or tissue transplantation.There are lot of benefits but also lot of shortcomings; immunosuppressant agents may beneurotoxic and there interaction with other drugs metabolized by CYP 450 may inducepsychopathological complications.The authors deal with psychiatric complication ofprednisone,ciclosporine and other immunosuppressive drugs. They also offer therapeutic possibilities inthese cases.

Key words:
organ transplantation - immunosuppressive drugs - psychiatric complications - prednisone - ciclosporine - CYP 450.

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