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Treatment of Cutaneous Mastocytosis


Authors: M. Péč 1;  P. Višňovský 2;  J. Péč 3;  L. Plank 4
Authors‘ workplace: Ústav lekárskej biológie JLF UK, Martin, prednosta RNDr. J. Dobiáš, CSc. 2Ústav farmakológie a toxikológie Farmaceutickej fakulty UK, Hradec Králové, prednosta prof. MUDr. Z. Fendrich, CSc. 3Klinika dermatovenerológie JFL UK, Martin, prednosta doc. MUDr. 1
Published in: Prakt. Lék. 2001; (2): 78-81
Category:

Overview

The authors investigated the treatment of 30 patients with cutaneous mastocytosis. In the course of six months to one year they observed as a result of treatment a 20-60 % regression of mastocytic infiltrates of the corium. The patients were treated locally by external corticosteroid preparations applied once or twice and by systemic treatment with ketotifene combined with H1 and H2 antihistaminics. Three patients who suffered in addition to cutaneous mastocytosis also from the systemic form of the disease used oral corticosteroids in doses of 0.5-1.0 mg/kg body weight/day. In none of the patients the disease developed into a life threatening form and in none of the patients complications of treatment of mastocytosis threatening the patient’s life were recorded.

Key words:
cutaneous mastocytosis - histology - corium - treatment.

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