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Idiopathic Hypoparathyreoi-dism with Celiac Disease – Diagnostic and Therapeutic Problem


Authors: K. Lukáš;  M. Lukáš
Authors‘ workplace: I. interní klinika FN, Olomouc, přednosta prof. MUDr. J. Lukl, CSc. 1 Interní ambulance Valašské Meziříčí 2 Oddělení imunologie FN, Olomouc, přednosta doc. MUDr. E. Weigl, CSc.
Published in: Prakt. Lék. 2000; (1): 408-412
Category:

Overview

A middle-aged woman developed gradually diseases where most probably the common denomina-tor is an autoimmune process. The authors describe the clinical condition persisting for sevenyears, where hypoparathyroidism was associated with coeliac disease which did not respond todietary measures. Malabsorption was manifested by a selective block for calcium absorption fromthe gut. The impaired conversion of vitamin D2 to D3 is of interest; it has obviously a multifactori-al etiology. The main problem is the patient´s tendency to respond by tachyphylaxis to oralvitamin D administration. The only effective therapeutic procedure apart from those listed is sofar parenteral administration of vitamin D3, calcitrol.

Key words:
Idiopathic hypoparathyroidism - Celiac disease - Malabsorption - Granulomatous

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