Exclusive enteral nutrition – first-line therapy of Crohn’s disease in children

Czech version

Authors: E. Karásková
Authors‘ workplace: Dětská klinika LF UP a FN Olomouc
Published in: Gastroent Hepatol 2015; 69(6): 531-535
Category:
doi: https://doi.org/10.14735/amgh2015531

Overview

Inflammatory bowel diseases include Crohn‘s disease and ulcerative colitis. Up to 20% of patients with Crohn’s disease are diagnosed before the age of 18 years. The onset of the disease in childhood is often accompanied by growth retardation and impaired bone metabolism. The therapeutic approach differs in certain aspects from the treatment of adult patients. Particularly, exclusive enteral nutrition is recommended as first-line therapy to induce remission in children with newly diagnosed Crohn’s disease. Over recent years this therapy has often replaced corticosteroids. According to available studies, this treatment induces endoscopic remission better than corticosteroids, while improving bone metabolism, growth and nutritional status. Exclusive enteral nutrition is generally well tolerated and with proper administration its complications and side effects areminimal.

Key words:
Crohn’s disease – child – enteral nutrition

The author declares he has no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE „uniform requirements“ for biomedical papers.

Submitted:
21. 10. 2015

Accepted:
6. 11. 2015

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