Osteoporosis in endocrinopathies
Authors:
Juraj Payer; Peter Jackuliak
Authors‘ workplace:
V. interná klinika LF UK a UNB, Nemocnica Ružinov, Bratislava
Published in:
Forum Diab 2021; 10(1): 4-9
Category:
Overview
Osteoporosis is now recognized, together with cardiovascular and oncology diseases as a civilization disease. It represents a significant growing, worldwide health problem. The high incidence of osteoporosis and fractures contribute significantly to morbidity, mortality and increased health care costs. We can divide osteoporosis in two main groups – primary and secondary osteoporosis. Secondary osteoporosis is due to a known or yet unidentified (asymptomatic) disease or long-term treatment, adversely affecting bone metabolism. So in primary osteoporosis as well as in the secondary osteoporosis it is usually a disorder associated with changes in hormone activity. The most common is the primary estrogen-deficient postmenopausal osteoporosis. However, osteoporosis is caused by a disorder of secretion of cortisol, growth hormone, thyroid, parathyroid or impaired secretion or insulin action. Except antiporotic treatment in all cases must be treated also the hormone disorder. The authors provide an overview of the root causes of endocrine conditional osteoporosis, its etiopathogenesis, clinical manifestations, diagnosis and treatment of basic principles.
Keywords:
endocrinopathies – hormonal changes – osteoporosis
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