Otrava etanolem a psychotropními látkami u případu s hnilobnými změnami
Authors:
Hiroshi Kinoshita 1; Naoko Tanaka 1; Mostofa Jamal 1; Mitsuru Kumihashi 1; Ayaka Takakura 1; T. Tobiume 1; Kunihito Tsutsui 2; Kiyoshi Ameno 1
Authors‘ workplace:
Department of Forensic Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan
1; Health Sciences, School of Nursing, Faculty of Medicine, Kagawa University, Kagawa, Japan
2
Published in:
Soud Lék., 60, 2015, No. 2, p. 25-27
Category:
Original Article
Overview
Je prezentován případ smrtelné otravy paroxetinem, flunitrazepamem a etanolem v terénu hnilobných změn. Kvantitativní toxikologická analýza vykázala, že koncentrace paroxetinu a 7-aminoflunitrazepamu ( metabolitu flunitrazepamu) ve vzorku femorální krve byla 0,28 µg/ml a 0.17 µg/ml. Také byla zjištěna hladina alkoholu 2,90 mg/ml a n-propanolu 0,10 mg/ml. Usuzujeme proto, že smrt nastala v důsledku vzájemné interakce paroxetinu, flunitrazepamu a etanolu. Bylo též uvažováno o vlivu hnilobných změn na forensní toxikologické vyhodnocení.
Klíčová slova:
flunitrazepam – etanol – paroxetine – plynová chromatografie s hmotnostní spektrometrií (GC/MS).
Sources
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Labels
Anatomical pathology Forensic medical examiner ToxicologyArticle was published in
Forensic Medicine
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