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Human papillomavirus infection (HPV) and pregnancy


Authors: Borek Sehnal 1;  Michael Jiří Halaška 1;  R. Vlk 1;  V. Drochýtek 1;  T. Pichlík 1;  Martin Hruda 1;  H. Robová 1;  Lukáš Rob 1;  R. Tachezy 2
Authors‘ workplace: Onkogynekologické centrum, Gynekologicko-porodnická klinika, Fakultní nemocnice Královské Vinohrady a 3. lékařské fakulty Univerzity Karlovy, Praha 1;  Katedra genetiky a mikrobiologie, Přírodovědecká fakulta BIOCEV, Univerzita Karlova, Praha 2
Published in: Epidemiol. Mikrobiol. Imunol. 73, 2024, č. 1, s. 37-50
Category:
doi: https://doi.org/10.61568/emi/11-6254/20240123/136241

Overview

Human papillomavirus (HPV) is the most common sexually transmitted viral infection worldwide, which may result in the development in benign lesions or malignant tumors. The prevalence of HPV infection is twice as high in pregnancy as in non-pregnant women. Additionally, there is a risk of vertical transmission of HPV from mother to fetus during pregnancy or childbirth. Various studies have reported an increased risk of adverse pregnancy outcomes in HPV-positive women, including miscarriage, preterm birth, premature rupture of membranes, preeclampsia, fetal growth restriction, and fetal death. HPV vaccination is not currently recommended during pregnancy. On the other hand, there is no evidence linking HPV vaccination during pregnancy with adverse pregnancy outcomes and termination of pregnancy is not justified in this case.

Keywords:

HPV – human papillomavirus– pregnancy complications – adverse pregnancy outcomes – vaccination in pregnancy


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Grantová podpora

Projekt Národního institutu virologie a bakteriologie (Program EXCELES, ID: LX22NPO5103) – financováno Evropskou unií – Next Generation EU.
Cooperatio program, Maternal and Childhood Care No. 207035,
3. lékařská fakulta Karlovy Univerzity.

Do redakce došlo dne 17. 8. 2023.

Adresa pro korespondenci:
as. MUDr. Borek Sehnal, Ph.D.
Gynekologicko-porodnická klinika
Fakultní nemocnice Královské Vinohrady
Šrobárova 1150/50
100 34 Praha 10
e-mail:
boreksehnal@seznam.cz

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