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Serological survey and vaccination against viral hepatitis A in health care providers at the Clinic of Infectious Diseases in Ostrava


Authors: L. Rožnovský 1;  A. Kloudová 2;  J. Dlhý 3;  I. Lochman 2;  M. Kovalská 4
Authors‘ workplace: Infekční klinika FNsP a ZSF OU, Ostrava 1;  Odbor imunologie a alergologie, Zdravotní ústav, Ostrava 2;  Odbor epidemiologie, KHS Královéhradeckého kraje, Hradec Králové 3;  Infekční klinika FNsP, Ostrava 4
Published in: Epidemiol. Mikrobiol. Imunol. 54, 2005, č. 3, s. 129-136

Overview

Study objective:
The health care providers of the Clinic of Infectious Diseases in Ostrava were screened for immunity to hepatitis A virus (HAV) in an attempt to provide vaccination against hepatitis A to non-immune persons.

Study subjects and Methods:
A cohort of 101 health care providers of the Clinic of Infectious Diseases, i.e. 10 physicians, 56 nurses and 35 nursing auxiliaries, were screened. Total anti-HAV antibodies were determined by ELISA and the subjects not reaching the protective level of anti-HAV antibodies were considered as non-immune. Vaccination against hepatitis A was recommended to all of the non-immune persons.

Results:
Immunity to HAV was detected in 41 (41 %) of 101 screened subjects. Immunity was increasing with age, being found in 8 % of subjects under 40 years of age and 59 % of older subjects, in 2 (20 %) physicians, 23 (41 %) nurses and 16 and nursing auxiliaries. Vaccination of 58 nonimmune subjects was conducted without complications.

Conclusion:
The prevalence rates of total anti-HAV antibodies in health care providers of the Clinic of Infectious Diseases showed a continuing upward trend with age and were practically the same as in the community.

Key words:
viral hepatitis A – immunity – prevalence – health care providers – vaccination.


Labels
Hygiene and epidemiology Medical virology Clinical microbiology
Topics Journals
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