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Histopatologická diagnostika kožních melanocytárních lézí

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Authors: Lumír Pock;  Alena Skálová
Published in: Čes.-slov. Patol., 60, 2024, No. 1, p. 12-34
Category: Reviews Article

Overview

Melanocytární léze jsou nestabilní tumory, jejichž genom a změny v něm determinují jejich morfologii a biologické vlastnosti. Mezi névy a melanomy jsou v různém smyslu atypické, intermediální léze. Na základě nových molekulárně-biologických poznatků bylo možné v jejich rámci vyčlenit tzv. melanocytomy. Článek poskytuje aktuální souhrn benigních, intermediálních, maligních a kombinovaných melanocytárních kožních lézí a nabízí praktická doporučení při jejich diagnostice.

Klíčová slova:

klasifikace – histopatologie – melanocytární léze – genetické alterace – dermatoskopicko-histopatologické korelace – melanocytomy – praktická diagnostická doporučení – léze intermediální

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