The changes and updates in the fifth edition of the WHO Classification of prostate tumors

Czech version

Authors: Ondrej Ondič ^1,2
Authors‘ workplace: Šiklův ústav patologie, Univerzita Karlova Praha, Lékařská fakulta Plzeň, Česká Republika ¹; Bioptická laboratoř, s. r. o., Plzeň, Česká republika ²
Published in: Čes.-slov. Patol., 58, 2022, No. 4, p. 205-206
Category: Reviews Article

Overview

The fifth edition of the WHO classification of prostate tumors provides new insight into prostate cancer pathogenesis supported by molecular data. It discards the terms low-grade PIN and high-grade PIN. The new entity „Treatment-related neuroendocrine prostatic carcinoma“ is introduced. The importance of the diagnosis of intraductal carcinoma is highlighted. The terminology of prostatic basocellular carcinoma is upgraded. Some cancer subtypes are being relocated to different chapters based on new findings. Also, the role of the prostate as an origin of hereditary cancer is stressed. Finally, the new therapeutic approaches are mentioned.

Keywords:

prostate – cancer – WHO classification 2022

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