Cytology of Ovarian cysts

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Authors: Jaroslava Dušková
Authors‘ workplace: Ústav patologie 1. LF UK a VFN, Praha
Published in: Čes.-slov. Patol., 55, 2019, No. 2, p. 107-111
Category: Reviews Article

Overview

Ovarian cysts are often found in both the clinically predicted and the unexpected context at the current level of imaging techniques. The cytological examination of the transvaginally obtained cystic fluid can help to diagnose the nature of the cystic lesion via identification the lining structures. It is essential to distinguish functional cysts (follicular, corpusluteal) and implantation (inclusion and endometrial) from tumour cysts (dermoid, epithelial ovarian tumours, cystic metastases). A part of the cystic lesions remains unspecified for the absence of the defining structures after the cytological examination. Nevertheless, for its minimal invasiveness, high negative predictive value proven, and the possibility of contributing to diagnosis of selected patients (frequently with contraindications for larger diagnostic procedures), this investigation maintains its position in collaboration of a clinical specialist and a pathologist.

Keywords:

ovarian cysts – cystic fluid cytology – follicular cysts – corpusluteal cysts – neoplastic ovarian cysts

Sources

1. Bednář B. Patologie. 2. přepr. a dopl. vyd. Praha: Avicenum, 1982, ss. 315-321.

2. Motlík K, Živný J. Patologie v ženském lékařství (1 ed.). Prague: 2001: 214-223.

3. Hangval H, Habibi H, Moshref A, Rahimi A. Case report of an ovarian hydatid cyst. J Trop Med Hyg 1979; 82(2): 34-35.

4. Sahu B, Regmi K. Hydatid cyst of ovary-a case report. Indian J Pathol Microbiol 1999; 42(4): 501-502.

5. Konar K, Ghosh S, Konar S, Bhattacharya S, Sarkar S. Bilateral ovarian hydatid disease--an unusual case. Indian J Pathol Microbiol 2001; 44(4): 495-496.

6. Brahima D, Alain Didier A, Gonat Serge Pacome D, et al. A rare case of ovarian filariasis in Abidjan. Case Rep Pathol 2016; 2016:4075162.

7. Powell G, Sarmah P, Sethi B, et al. Enterobius vermicularis infection of the ovary Case Reports 2013; 2013:bcr2013201146.

8. Tas EE, Yegin Akcay GF, Yildirim F, Yavuz F. Coexisting primary ovarian and omental hydatid disease mimicking an ovarian neoplasm: A case report. Int J Gynecol Pathol 2018; 37(3): 301-304.

9. Gigase PL, Vanderputte SR. Presence d‘oeufs de Schistosoma haematobium dans un teratome ovarien. Ann Soc Belg Med Trop 1980; 60(1): 107-109.

10. Bamford SB, Mitchell GW, Jr., Bardawil WA, Cassin CM. Vaginal cytology in polycyctic disease. Acta Cytol 1965; 9: 322-327.

11. De Brux J, Dupre-Froment J, Mintz M. Cytologie des kystes annexiels ponctionnes sous coelioscopie et culdoscopie. Arch Anat Pathol (Paris) 1967; 15(Suppl:83-87.

12. Mintz M, Dupre-Froment J, De Brux J. Ponctions de 94 kystes para-uterins sous coelioscopie et etude cytologique des liquides. Gynaecologia 1967; 163(2): 61-76.

13. Gauthier F, Valayer J, Bienayme J. Tumeurs et kystes de l‘ovaire du nouveau-ne, du nourrisson et de l‘enfant. Chir Pediatr 1979; 20(2): 75-83.

14. Ganjei P, Dickinson B, Harrison T, Nassiri M, Lu Y. Aspiration cytology of neoplastic and non-neoplastic ovarian cysts: Is it accurate? Int J Gynecol Pathol 1996; 15(2): 94-101.

15. Gupta N, Rajwanshi A, Dhaliwal LK, et al. Fine needle aspiration cytology in ovarian lesions: An institutional experience of 584 cases. Cytopathology 2012; 23(5): 300-307.

16. Koss LG. Diagnostic cytology and its histopathologic bases (4th ed.). Philadelphia: Lippincott; 1992: 618-642.

17. De May RM. The art and science of cytopathology (1st ed.). Chicago: ASCP Press; 1995: 1163-1176.

18. Zajicek J. Cytology of infradiaphragmatic organs. 3. Ovary. Monogr Clin Cytol 1979; 7(54-56.

19. Wojcik EM, Selvaggi SM. Fine-needle aspiration cytology of cystic ovarian lesions. Diagn Cytopathol 1994; 11(1): 9-14.

20. Sutton C. The limitations of laparoscopic ovarian biopsy. J Obstet Gynaecol Br Commonw 1974; 81(4): 317-320.

21. Collet B, Billeaud C, Diard F, Bondonny JM, Sandler B. Le kyste de l‘ovaire du nouveau-ne: quelle attitude adopter? (a propos de 8 observations). Pediatrie 1987; 42(7): 557-561.

22. De Crespigny LC, Robinson HP, Davoren RA, Fortune D. The ‚simple‘ ovarian cyst: Aspirate or operate? Br J Obstet Gynaecol 1989; 96(9): 1035-1039.

23. Greenebaum E, Mayer JR, Stangel JJ, Hughes P. Aspiration cytology of ovarian cysts in in vitro fertilization patients. Acta Cytol 1992; 36(1): 11-18.

24. Khaw KT, Walker WJ. Ultrasound guided fine needle aspiration of ovarian cysts: Diagnosis and treatment in pregnant and non-pregnant women. Clin Radiol 1990; 41(2): 105-108.

25. Sheombar ES, Logmans A, Verhoeff A, Van Lent M. Ovarian cysts, cytology and histology: A conflicting story. Eur J Obstet Gynecol Reprod Biol 1993; 52(1): 41-44.

26. Koutlaki N, Nikas I, Dimitraki M, et al. Transvaginal aspiration of ovarian cysts: Our experience over 121 cases. Minim Invasive Ther Allied Technol 2011; 20(3): 155-159.

27. Lin DM, Barkan GA, Chatt G, Park JW, Gattuso P. Vaginal fine-needle aspiration: A useful alternative to biopsy. Diagn Cytopathol 2016; 44(8): 665-669.

28. Zhou AG, Levinson KL, Rosenthal DL, Vandenbussche CJ. Performance of ovarian cyst fluid fine-needle aspiration cytology. Cancer Cytopathol 2018; 126(2): 112-121.

29. Duke D, Colville J, Keeling A, et al. Transvaginal aspiration of ovarian cysts: Long-term follow-up. Cardiovasc Intervent Radiol 2006; 29(3): 401-405.

30. Firouzabadi RD, Sekhavat L, Javedani M. The effect of ovarian cyst aspiration on ivf treatment with gnrh. Arch Gynecol Obstet 2010; 281(3): 545-549.

31. Puligandla PS, Laberge JM. Lethal outcome after percutaneous aspiration of a presumed ovarian cyst in a neonate. Semin Pediatr Surg 2009; 18(2): 119-121.

32. Mccluggage WG, Patterson A, White J, Anderson NH. Immunocytochemical staining of ovarian cyst aspirates with monoclonal antibody against inhibin. Cytopathology 1998; 9(5): 336-342.

33. Davila RM. Cytology of benign cystic uterine adnexal masses. Acta Cytol 1993; 37(3): 385-390.

34. Sharma A, Sengupta P, Mondal S, Raychaudhuri G. Hydatid cyst of ovary mimicking ovarian neoplasm with its imprint cytology. Am J Case Rep 2012; 13: 276-278.

35. Selhi PK, Grover S, Narang V, et al. Intraoperative diagnosis of hydatid cyst of the ovary masquerading as tumor. Diagn Cytopathol 2017; 45(3): 267-269.

36. Ozcan HC, Ugur MG, Gunduz R, Bozdag Z, Kutlar I. Parasitic omental ovarian dermoid tumour mimicking an adnexal mass: A report of two very unusual cases. Turk J Obstet Gynecol 2015; 12(4): 251-253.

37. Chitrakar NS, Suwal S, Neupane S. Bilateral ovarian teratoma: One parasitic twisted in-situ and another parasitic at the hepato renal space. J Nepal Health Res Counc 2015; 13(30): 166-168.

38. Cole L, Mount S, Nuzzo E, Wong C. Aspiration cytology of ovarian cystic masses: Histologic correlation and review of the literature. Acta Cytol 2011; 55(1): 19-25.

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Article was published in

Czecho-Slovak Pathology

2019 Issue 2