Commentary on the Proposal of a New WHO Classification of Non-Hodgkin’sMalignant Lymphomas

Overview

Newly proposed WHO classification of non-Hodgkin’s malignant lymphomas (17) is based on theprinciples of the REAL classification. According to these principles, the classification representsa list of tumor disease entities, which have been accepted by clinical practice. The entities aredefined by a multiparameter approach, which involves morphology, immunophenotype and geno-type of the tumor cells, as well as clinical presentation and course of the disease requiring anappropriate therapy. All the categories of the WHO classification are briefly described, togetherwith their relationship to the categories of the Kiel classification.

Key words:
Classification of malignant lymphomas - B and T/NK non-Hodgkin’s lymphomas -