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Renal Angiomyolipoma with a Clear Cell Component


Authors: O. Hes 1;  F. Havlíček 2;  M. Michal 1
Authors‘ workplace: Šiklův patologicko anatomický ústav Fakultní nemocnice, Plzeň, přednosta prof. MUDr. F. Fakan, CSc. 2 Patologicko-anatomické oddělení Nemocnice Rudolfa a Stefanie, Benešov, primář MUDr. F. Havlíček 1
Published in: Čes.-slov. Patol., , 1999, No. 3, p. 94-97
Category:

Overview

Case report of a 52-year-old woman with angiomyolipoma of the left kidney. The tumor hadappearance of a typical angiomyolipoma predominantly composed of spindle cells, some epithelio-id cells and few large hyalinized vessels. Adipose tissue was concentrated into small foci. Unusualpresence of large cells with a clear fine granular cytoplasm closely resembled cells of the „sugartumor“ of the lung. Epithelioid cells and occasionaly spindle cells were HMB45 positive. A minori-ty of cells also coexpressed S100 protein. Clear cells were usually strongly positive for HMB45 too.Our findings supported consideration of a close relation between clear cell („sugar“) tumor of thelung and angiomyolipoma.

Key words:
clear cell angiomyolipoma - kidney - clear cell tumor

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Anatomical pathology Forensic medical examiner Toxicology
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