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Low Grade Malignant Fibromyxoid Sarcoma


Authors: K. Hušek;  P. Janíček *;  O. Jelínek *
Authors‘ workplace: I. patologickoanatomický ústav LF MU, Brno, přednosta prof. MUDr. J. Buček, CSc. *I. ortopedická klinika LF MU, Brno, přednosta MUDr. R. Moster
Published in: Čes.-slov. Patol., , 1998, No. 4, p. 139-141
Category:

Overview

Two cases of low-grade fibromyxoid sarcoma are presented. In a 31-year-old male the tumour arouse in the scapular soft tissues and local recurrence occurred. In a female of 45, the neoplasm was located in the thigh. Histologically, the neoplasms with low cellularity of deceptively benign- appearing small fibroblastic spindle cells demonstrated alternating dense fibrous and loose myxo- id areas, showing a mainly whorled and swirling growth pattern. In myxoid areas a prominent vascular component was present. Mitoses and cellular atypia were absent. Tumor cells showed staining with anti-vimentin and occasionally anti-actin antibodies. As a distinctive soft-tissue sarcoma, low-grade fibromyxoid sarcoma had to be distinguished from variety of benign and malignant soft tissue tumours such as neurofibroma, liposarcoma, myxoid MFH and others.

Key words:
soft tissue neoplasm - low-grade fibromyxoid sarcoma - sarcoma

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Anatomical pathology Forensic medical examiner Toxicology
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