ASYNCHRONOUS BILATERAL SEMINOMA BASED ON INTRATUBULAR GERM CELL NEOPLASIA UNCLASSIFIED TYPE
Authors:
Jakub Musil; Daniel Bulíř; Jan Jandejsek
Authors‘ workplace:
Urologické oddělení, Oblastní nemocnice Kolín a. s.
Published in:
Ces Urol 2015; 19(2): 157-162
Category:
Case report
Overview
Objective:
We are presenting a case report of young man who developed an asynchronous bilateral seminoma based on an intratubular germ cell neoplasia of unclassified type (IGCNU).
Case report:
A patient, with history of a stage I seminoma of the left testis, based on an IGCNU of the left testis, after a radical orchidectomy and adjuvant radiotherapy, was referred to the urology clinic with a suspected tumor of the right testis. A testicular biopsy was made and the histological examination showed an IGCNU. A radical orchidectomy was performed and a seminoma was found.
Conclusion:
IGCNU is a precursor lesion of germ cell testicular tumors. Treatment of the IGCNU includes radiotherapy or chemotherapy with cisplatin. Surveillance remains an option for those with a solitary testicle who wish to preserve fertility and endocrine function.
A contralateral testicular biopsy, in patients with a history of germ cell tumors, should be made in cases of cryptorchidism, poor spermatogenesis, and testicular atrophy with a testicular volume of less than 12 ml. Biopsy is also recommended in patients with testicular microlithiasis and history of ITGCNU.
Key words:
Intratubular germ cell neoplasia unclassified – ITGCNU, seminoma, radical orchidectomy, testicular microlithiasis.
Sources
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Paediatric urologist Nephrology UrologyArticle was published in
Czech Urology
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