#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

ICON – a summary of the latest recommendations for management of bronchial asthma in children


Authors: L. Hoňková;  K. Beránková;  P. Pohunek
Authors‘ workplace: Pediatrická klinika UK 2. LF a FN Motol, Praha přednosta prof. MUDr. J. Lebl, CSc.
Published in: Čes-slov Pediat 2014; 69 (1): 21-28.
Category: Reviews

Overview

Bronchial asthma is the leading chronic lower respiratory tract disease in children. Major advances were made in understanding its pathophysiology and pathogenesis as well as in asthma therapy. Nevertheless, the disease remains poorly controlled in significant proportion of patients. In the past years several national and international documents focused on childhood asthma were published. The focus is on implementing the latest advances into clinical practice.

The ICON (International Consensus ON pediatric asthma) document, published in 2012, is a collaborative work of leading pediatric allergists and pulmonologists. Its aim is to compare existing recommendations and unify their conclusions. Main topics of the ICON document are reviewed in this article.

Key words:
bronchial asthma, asthma phenotypes, children, diagnosis, therapy


Sources

1. Papadopoulos NG, Arakawa H, Carlsen KH, et al. International Consensus ON (ICON) Pediatric Asthma. Allergy 2012; 67: 976–997.

2. Global Strategy for Asthma Management and Prevention. The Global Initiative for Asthma, 2011; http://www.ginasthma.org/ uploads/users/fi les/GINA_Report2011_May4.pdf.

3. Expert Panel Report 3: Guidelines for the Diagnosis and Management Asthma. National Hearth, Lung, and Blood Institute (US), Bethesda, 2007. http://www.nhlbi.nih.gov/guidelines/ asthma/asthgdln.pdf.

4. Bacharier LB, Boner A, Carlsen KH, et al. Diagnosis and treatment of asthma in childhood: a PRACTALL Consensus Report. Allergy 2008; 63: 5–34.

5. Bossé Y, Paré PD, Seow CY. Airway wall remodeling in asthma: from the epithelial layer to the adventitia. Current Allergy and Asthma Reports 2008; 8: 357–366.

6. Regamey N, Jeffery PK, Alton EWFW, et al. Airway remodelling and its relationship to inflammation in cystic fibrosis. Thorax 2010; 66: 624–629.

7. Pohunek P, Warner JO, Turzíková J, et al. Markers of eosinophilic inflammation and tissue remodelling in children before clinically diagnosed bronchial asthma. Pediatr Allergy Immunol 2005; 16: 43–51.

8. Saglani S, Payne DN, Zhu J, et al. Early detection of airway wall remodeling and eosinophilic inflammation in preschool wheezers. Am J Respir Crit Care Med 2007; 176: 858–864.

9. Gilliland DF, Yu-Fen L, Peters MJ. Effects of maternal smoking during pregnancy and environmental tobacco smoke on asthma and wheezing in children. Am J Respir Crit Care Med 2001; 163: 429–436.

10. Bozzetto S, Carraro S, Giordano G, et al. Asthma, allergy and respiratory infections: the vitamin D hypothesis. Allergy 2012; 67: 10–17.

11. Global Strategy for the Diagnosis and Management of Asthma in Children 5 Years and Younger. The Global Initiative for Asthma, 2009; http://www.ginasthma.org/uploads/users/fi les/ GINA Under5 2009 CorxAug11.pdf.

12. Castro-Rodríguez JA, Holberg CJ, Wright AL, et al. A clinical index to define risk of asthma in young children with recurrent wheezing. Am J Respir Crit Care Med 2000; 162: 1403–1406.

13. Dweik RA, Boggs PB, Erzurum SC, et al. An official ATS clinical practice guideline: Interpretation of Exhaled Nitric Oxide Levels (FENO) for Clinical Applications. Am J Respir Crit Care Med 2011; 184: 602–615.

14. McKean M, Ducharme F. Inhaled steroids for epizodic viral wheeze of childhood. Cochrane Database Syst Rev 2000;(2):CD001107.

15. Lipworth BJ. Leukotriene – receptor antagonists. Lancet 1999; 353: 57–62.

16. Scaparrotta A, Di Pillo S, Attanasi M, et al. Montelukast versus inhaled corticosteroids in the management of pediatric mild persistent asthma. Multidiscip Respir Med 2012; 7: 13.

17. Stelmach I, Grzelewski T, Majak P, et al. Effect of different antiasthmatic treatments on exercise-induced bronchoconstriction in children with asthma. J Allergy Clin Immunol 2008; 121: 383–389.

18. Nelson HS, Weiss ST, Bleecker ER, et al. The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol. Chest 2006; 129: 15–26.

19. Salpeter SR, Buckley NS, Ormiston TM, et al. Meta-analysis: Effect of Long-Acting Beta-Agonists on Severe Asthma Exacerbations and Asthma-Related Deaths. Ann Intern Med 2006; 144: 904–912.

20. Ducharme FM, Lemire C, Noya FJ, et al. Preemptive use of high-dose fluticasone for virus-induced wheezing in young children. N Engl J Med 2009; 360: 339–353.

Labels
Neonatology Paediatrics General practitioner for children and adolescents
Topics Journals
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#