Assessment of Arterial Wall Stiffness by Measurement of Pulse Wave Velocity in Children
Authors:
K. Šamudovská; Ľ. Podracká
Authors‘ workplace:
1. Klinika detí a dorastu LF UPJŠ a DFN, Košice
prednostka prof. MUDr. Ľ. Podracká, CSc.
Published in:
Čes-slov Pediat 2010; 65 (7-8): 459-464.
Category:
Review
Overview
Arterial stiffness is an independent predictor of cardiovascular risk in both adult and pediatric population. Mechanism of arterial rigidity genesis is a complex process characterized by the interaction between inflammatory reaction, endothelium and vascular smooth muscle cells leading to the structural changes of the arterial wall with reduction of its elasticity. Recently, a measurement of pulse wave velocity (PWV) has been proved a simple noninvasive method useful for assessment of the arterial stiffness, indirectly reflecting the elasticity of aorta. PWV in children is greatly influenced by age, gender and blood pressure variation.
PWV measurement provides a useful clinical information about the risk of vascular damage and might be a relevant tool for stratification of cardiovascular risk.
Key words:
pulse wave velocity, cardiovascular risk factor, arterial stiffness
Sources
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Labels
Neonatology Paediatrics General practitioner for children and adolescentsArticle was published in
Czech-Slovak Pediatrics
2010 Issue 7-8
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