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Autoimmune Bullous Diseases Part II: Subepidermal Autoimmune Bullous Dermatoses


Authors: H. Jedličková
Authors‘ workplace: I. dermatovenerologická klinika FNUSA a LF Masarykovy univerzity, Brno přednostka prof. MUDr. Hana Jedličková, Ph. D.
Published in: Čes-slov Derm, 98, 2023, No. 4, p. 184-195
Category: Reviews (Continuing Medical Education)

Overview

Autoimmune bullous dermatoses (AIBD) are rare, potentially fatal diseases of the skin and mucous membranes. According to the level of blister formation, we divide them into the group of pemphigus withintraepidermal blister and the group with subepidermal blister, which includes bullous pemphigoid, pemphigoid gestationis, mucous membrane pemphigoid, linear IgA dermatosis, epidermolysis bullosa acquisita and dermatitis herpetiformis. This review discusses subepidermal AIBD, with a focus on current diagnostics and recommended therapy. Individual diseases are distinguished by target autoantigens, frequency, clinical picture, response to therapy and prognosis. It is very important to have comprehensive diagnostics that differentiates the individual types of the disease and determines the best therapeutic procedure.

Keywords:

bullous pemphigoid – pemphigoid gestationis – mucous membrane pemphigoid – linear IgA dermatosis – epidermolysis bullosa acquisita – dermatitis herpetiformis – diagnosis – therapy


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Do redakce došlo dne 24. 3. 2023.

Adresa pro korespondenci: prof. MUDr. Hana Jedličková, Ph.D.

1. dermatovenerologická klinika LF a FN u sv. Anny v Brně

Centrum ERN pro bulózní onemocnění

Pekařská 664/53 602 00 Brno

e-mail: hana.jedlickova@fnusa.cz

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