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Calcification and Ossification in Dermatology and Dermatopathology

Czech version

Authors: M. Důra;  J. Štork
Authors‘ workplace: Dermatovenerologická klinika 1. LF UK a VFN, přednosta prof. MUDr. Jiří Štork, CSc.
Published in: Čes-slov Derm, 99, 2024, No. 2, p. 48-60
Category: Reviews (Continuing Medical Education)

Overview

Pathological calcification in the skin and subcutaneous tissue is relatively heterogenous issue. From the etiopathogenetic point of view, the pathological calcifications are divided into dystrophic, metastatic, idiopathic, and iatrogenic type. Calciphylaxis is distinguished as a distinctive type.

Ectopic ossification in dermatology is a rare phenomenon, which arises as an isolated finding or as a part of the range of tumours, in which the ossification is a typical feature.

The article summarizes the topic of the pathological calcification and the ectopic ossification in dermatology and dermatopathology. The paper presents the definition, the brief description of the etiopathogenesis and the list of the most common diseases connected to the particular types of the pathological calcium deposition in the skin, the subcutaneous tissue and the soft tissue. The review also summarizes the problematics of the osteoma cutis from the view of the clinical picture and the histopathology. Finally, the short summary of the diagnostic and therapeutic alternatives is discussed.

Keywords:

dystrophic calcification – metastatic calcification – idiopathic calcification – calciphylaxis – ossification – osteoma cutis

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Poděkování

Autoři děkují MUDr. Mateji Kuchárovi z Radiodiagnostické kliniky 1. LF UK a VFN za laskavé poskytnutí radiologické dokumentace.

Do redakce došlo dne 8. 3. 2024.

Adresa pro korespondenci:
MUDr. Miroslav Důra, Ph.D.
Dermatovenerologická klinika 1. LF UK a VFN
U Nemocnice 499/2 128 00 Praha 2
e-mail: miroslav.dura@lf1.cuni.cz

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