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Obliterative Vasculopathy in Dermatology

Czech version

Authors: O. Kodet 1,2
Authors‘ workplace: Dermatovenerologická klinika 1. LF UK a VFN, Praha přednosta prof. MUDr. Jiří Štork, CSc. 1;  Anatomický ústav 1. LF UK, Praha přednosta doc. MUDr. Ondřej Naňka, Ph. D. 2
Published in: Čes-slov Derm, 99, 2024, No. 1, p. 3-17
Category: Reviews (Continuing Medical Education)

Overview

Obliterative vasculopathies in dermatology represent a heterogeneous group of diseases with different pathogenesis. These are conditions of non-inflammatory occlusion of the vascular lumen with subsequently induced ischemia of the tissue (skin). In the current nomenclature, we also encounter the term cutaneous microvascular occlusive syndromes, which better characterize the involvement of skin vessels. Diseases that are responsible for occlusive syndromes include platelet pathology, the presence of cryoglobulins, infections affecting the vessel wall, embolisation (e.g. cholesterol), coagulopathy (antiphospholipid syndrome), or diseases accompanying chronic kidney failure (calciphylaxis). Possible skin manifestations include ulceration, necrotic lesions, livedo racemosa, and retiform purpura. The work provides a comprehensive view of the complex issue of these conditions and points to skin manifestations that are considered as manifestations of vasculitis in routine practice.

Keywords:

obliterative vasculopathy – microvascular occlusive syndromes – livedo reticularis – livedo racemosa – retiform purpura – thrombocytopathy – cryoglobulins – calciphylaxis

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Do redakce došlo dne 19. 2. 2024.

Adresa pro korespondenci:
doc. MUDr. Ondřej Kodet, Ph.D.
Dermatovenerologická klinika 1. LF UK a VFN
U Nemocnice 499/2 128 00 Praha 2
e-mail: ondrej.kodet@lf1.cuni.cz

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