Bullous Pemphigoid after COVID-19 Vaccination. Two Cases Report
Authors:
M. Komorousová; M. Novák; P. Cetkovská
Authors‘ workplace:
Dermatovenerologická klinika FN a LF UK, Plzeň, přednosta prof. MUDr. Karel Pizinger, CSc.
Published in:
Čes-slov Derm, 97, 2022, No. 3, p. 125-129
Category:
Case Reports
Overview
Bullous pemphigoid represents the most common autoimmune subepidermal blistering disease of the skin. It usually develops in the elderly population. Several factors have been implicated in the pathogenesis, such as trauma, ultraviolet therapy and drugs. Rarely, case reports describe the association of vaccination with the onset of pemphigoid. We report new onset of bullous pemphigoid and deterioration of previously diagnosed pemphigoid in two patients after the second dose of mRNA COVID-19 vaccination.
Keywords:
bullous pemphigoid – COVID-19 vaccination
Sources
1. AGHARBI, F. Z., ELJAZOULY, M., BASRI, G., et al. Bullous Pemphigoid induced by the AstraZeneca COVID-19 vaccine. Annales de dermatologie et de vénéréologie, 2021, doi.org/10.1016/j.annder. 2021.07.008.
2. DAMIANI, G., PACIFICO, A., PELLONI, F., IORIZZO, M. The first dose of COVID-19 vaccine may trigger pemphigus and bullous pemphigoid flares: is the second dose therefore contraindicated? J Eur Acad Dermatol Venereol. 2021, 35, e645-e647. https://doi.org/10.1111/jdv.17472.
3. ERBAGCI, Z. Childhood bullous pemfigoid following hepatitis B immunization. Journal of Dermatology, 2002, 2, p. 781–785.
4. KASPERKIEWICZ, M., BEDNAREK, M., TUKAJ, S. Circulating anti-SARS-CoV-2 antibodies do not cross react with pemphigus or pemphigoid autoantigens. Front Med, 2021, vol. 8, article 807711, p. 1–3.
5. KRIDIN, K., LUDWIG, R. J. The growing incidence of bullous pemfigoid: overview and potential explanations . Front Med (Lausanne) 2018, 5, p. 220.
6. LIU, S. D., CHEN, W. T., CHI, C. C. Association Between Medication Use and Bullous Pemphigoid: A Systematic Review and Meta-analysis. JAMA Dermatol. 2020, 156(8), p. 891–900. doi:10.1001/jamadermatol.2020.1587
7. MURRELL, D. F. Blistering diseases. Berlin Heidelberg: Springer-Verlag, 2015, 752 p.
8. NAKAMURA, K., KOSANO, M., SAKAI, Y. et al. Case of bullous pemphigoid following coronavirus disease 2019 vaccination. Journal of Dermatology, 2021, doi: 10.1111/1346-8138.16170.
9. PÉREZ-LÓPEZ, I., MOYANO-BUENO, D., RUIZ- -VILLAVERDE, R. Bullous pemphigoid and COVID- 19 vaccine. Med Clin (Barc). 2021, https:/doi. org/10.1016/j.medcli.2021.05.005.
10. TOMAYKO, M. M., DAMSKY, W., FATHY, R., et al. Subepidermal blistering eruption, including bullous pemphigoid, following COVID-19 vaccination. J Allergy Clin Immunol. 2021,148, p. 750–751.
11. PINKOVÁ, B., BUČKOVÁ, H., JEDLIČKOVÁ, H., FEIT, J. Bulózní pemfigoid vyvolaný očkováním. Čes-slov Derm, 2013, 88, č.3, s.128–131.
Labels
Dermatology & STDs Paediatric dermatology & STDsArticle was published in
Czech-Slovak Dermatology
2022 Issue 3
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