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Severe Drug Eruptions


Authors: H. Tomková 1;  J. Štork 2
Authors‘ workplace: Kožní oddělení, Krajská nemocnice T. Bati, a. s., Zlín přednosta prim. MUDr. Jan Šternberský, CSc. 1;  Dermatovenerologická klinika, 1. LF UK a VFN Praha přednosta prof. MUDr. Jiří Štork, CSc. 2
Published in: Čes-slov Derm, 88, 2013, No. 5, p. 203-212
Category: Reviews (Continuing Medical Education)

Overview

The authors summarize the most severe drug eruptions, namely DRESS syndrome, acute generalized exanthematous pustulosis, Stevens-Johnson syndrome and toxic epidermal necrolysis. Both clinical aspects and current knowledge of etiopathogenesis of these disorders are discussed. Diagnostics, treatment and possible complications are also highlighted.

Key words:
drug eruption – DRESS syndrome – acute generalized exanthematous pustulosis – Stevens-Johnson syndrome – toxic epidermal necrolysis


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