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Frequency of Soya Allergy in Atopic Patients Older than 14 Years


Authors: J. Čelakovská 1;  K. Ettlerová 2;  K. Ettler 1;  J. Vaněčková 1;  J. Bukač 3
Authors‘ workplace: Klinika nemocí kožních a pohlavních FN a LF UK Hradec Králové přednosta doc. MUDr. Karel Ettler, CSc. 1;  Ambulance klinické imunologie a alergologie, Hradec Králové vedoucí MUDr. Květuše Ettlerová 2;  Ústav lékařské biofyziky LF UK Hradec Králové přednosta doc. Ing. Josef Hanuš, CSc. 3
Published in: Čes-slov Derm, 85, 2010, No. 1, p. 14-20
Category: Clinical and laboratory Research

Overview

The soya proteins are considered important food and aeroallergens. The food allergy to soya represents an increasing problem in many countries. Despite this fact, the overall information on soya allergy is rare. Recently, only a few papers on soya allergy have been published. It seems that the patients with bronchial asthma and peanut allergy (with early allergic reactions: oral allergy syndrome or respiratory problems) are at high risk of severe reaction after soya ingestion.

The occurrence of early reactions to soya, the sensitivity of diagnostic methods and the relation to pollen and peanut allergy (early reactions) and to asthma bronchiale in patients older than14 years of age suffering from atopic eczema were evaluated in our study. In all 175 patients the complex dermatological and allergological examination of possible food allergy was performed.

The food allergy to soya, most often presented as an oral allergy syndrome, occurred nearly in 3% of patients. Positive specific IgE antibodies (serum specific antibodies, skin prick tests) with no clinical manifestation of soya allergy recorded in 23% of patients were evaluated as probable cross reactions to pollen. The skin prick test proved the best sensitivity (80%), followed by the atopy patch test (40%), the sensitivity of specific IgE was calculated to 20% in our study. Our study confirmed the relation of the severity of soya allergy to the peanut and pollen allergy. Though the interpretation of positive tests for soya allergy should regard signs of atopy. The patients suffering from atopic eczema together with bronchial asthma and severe peanut allergy seem to be at risk of developing severe reaction to soya without having any previous soya allergy.

Key words:
soya allergy – atopic eczema – pollen allergy – peanut allergy


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