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Onychomycoses Caused by Onychocola canadensis in the Slovak Republic


Authors: A. Volleková 1,2;  J. Őlvédyová 3;  T. Špačinská 4;  M. Lisalová 2
Authors‘ workplace: Katedra dermatovenerológie FZŠŠ SZU, Bratislava vedúca katedry doc. MUDr. K. Kolibášová, PhD, mim. prof. 1;  Mykologické oddelenie HPL s. r. o., Bratislava riaditeľ HPL s. r. o. MUDr. J. Hanzen 2;  Neštátna dermatovenerologická ambulancia, Malacky 3;  Neštátna dermatovenerologická ambulancia, Bratislava 4
Published in: Čes-slov Derm, 84, 2009, No. 3, p. 139-144
Category: Clinical and laboratory Research

Overview

In the years 2007 and 2008 we identified Onychocola canadensis, the slow-growing micromyceta, from the toenails of five (4 females, 1 male) patients of age from 44 to 61 years. Numerous fungal colonies (mostly in pure culture), repeated isolation of the same fungus from one patient despite of therapy for 2 months, microscopically thinner hyphae and a lot of hyaline to brownish oval-barrel shaped arthroconidia found in nail samples confirmed the mentioned species as a causative agent of onychomycoses. In the first patient with partial distolateral type of onychomycosis the terbinafine administration for 3 months and in the second one, with extensive nail involvement, therapy with terbinafine in dose of 250 mg a day for 4 months in combination with long term application of topical antifungal solution (ciclopiroxolamine) was successful. These are the first documented cases of rare O. canadensis onychomycosis seen in the Slovak republic.

Key words:
onychomycosis – Onychocola canadensis – terbinafine – ciclopiroxolamine


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