Panniculitis after Injection of Silicone

Czech version

Authors: M. Kofroňová; K. Pizinger
Authors‘ workplace: Dermatovenerologická klinika LF UK a FN Plzeň přednosta prof. MUDr. K. Pizinger, CSc.
Published in: Čes-slov Derm, 82, 2007, No. 2, p. 87-90
Category: Case Reports

Overview

Panniculitis may develop after subcutaneous injection of exogenous substances during cosmetic procedures. After silicone or paraffin application so-called siliconoma or paraffinoma may occur with latency period up to 10–20 years.

In 31-year-old woman the multiple very tender red nodules and diffuse firm swelling of breasts appeared 18 months after injection of unknown substance (probably silicone) into both breasts. Reccurent fever and lymphadenopathy also developed. Histological examination revealed multiple vacuoles of swiss cheese pattern in the dermis and subcutaneous fat, marked fibrosis and lymphohistiocytic infiltrates. Administration of systemic steroids had partial effect, however, radical surgery will be probably necessary in this serious case.

Key words:
panniculitis – exogenous material

Labels

Dermatology & STDs Paediatric dermatology & STDs

Diagnostics of Classical Venereal Diseases

Inflammatory Changes, Androgen and Retinoid Receptors Expression in Acne Patients Treated with Isotretinoin

Comparative Study of Acne Treatment with Vaccines and Systemic Antibiotics. Part 2: Characteristics of Bacterial Strains Isolated from Acne Lesions and their Antibiotic Resistance

Naevus Hypermelanoticus

Article was published in

Czech-Slovak Dermatology

2007 Issue 2