Management of preterm prelabor rupture of membranes with respect to the inflammatory complications – our experiences

Czech version

Authors: M. Kacerovský ¹; I. Musilová ^1,2
Authors‘ workplace: Porodnická a gynekologická klinika LF UK a FN, Hradec Králové, přednosta doc. MUDr. J. Špaček, Ph. D., IFEPAG ¹; Porodnická a gynekologická klinika, Krajská nemocnice, Pardubice, přednosta doc. MUDr. M. Koštál, CSc. ²
Published in: Ceska Gynekol 2013; 78(6): 509-513
Category: Original Article

Overview

Objective:
Preterm prelabor rupture of membranes is responsible for approximately one third of all preterm deliveries. The most common complications associated with this pregnancy pathology are microbial invasion of the amniotic cavity, intraamniotic inflammation, intraamniotic infection and histological chorioamnionitis. This article explains these complicatinos and their relation to the optimal management of preterm prelabor rupture of membranes.

Design:
Overview study.

Setting:
Department of Obstetrics and Gynecology, Charles University in Prague, Faculty of Medicine and University Hospital Hradec Kralove.

Methods:
To analyze current knowledge and our own experiences regarding inflammatory complications of preterm prelabor rupture of membranes.

Conclusion:
Inflammatory complications of preterm prelabor rupture of membranes are associated with risk of development of early onset sepsis. Nevertheless, gestational age is a main confounder affecting neonatal morbidity and mortality.

Keywords:
preterm delivery – intraamniotic inflammation – intraamniotic infection – chorioamnionitis

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