Correlation of Maximum Urethral Closure Pressure andValsalva Leak-Point Pressure in Patients with GenuineStress Incontinence

Overview

Objective:
The aim of our study was to fi nd correlation between Valsalva leak-point pressure(VLPP) and cough leak-point pressure (CLPP) and to determine whether water perfusion maximumurethral closure pressure (MUCP) correlates with Valsalva leak-point pressure (VLPP).Design: Cross-sectional clinical study.Settings: Gynecological and Obstetric Clinic, 1st Medical Faculty, Charles University and GeneralFaculty Hospital, Prague.Material and Methods: Thirty women with previously untreated GSI were recruited to participatein a clinical study. Their mean age was 56.9, mean body mass index (BMI) 27.6, and mean parity1.8. As part of the urethral pressure profi le we determined MUCP and functional length (FUL) ofthe urethra. VLPP and CLPP were assessed during US examination using an ultrasound contrastmedium and the color Doppler velocity (CDV). Funneling was described as the increase in distancebetween the inner edges of proximal urethra during Valsalva maneuver.Results: We did not fi nd statistically signifi cant differences in the mean value of VLPP and CLPP.The mean value of VLPP was 51.6 cm H2O (SD=26.5) and CLPP 53.1 cm H2O (SD=25.5). The meanvalues of MUCP were 39.7 cm H2O (SD=22.1) with 500 ml and 41.5 cm H2O (SD=22.7) with 300 mlof sterile saline; the difference between them is not statistically signifi cant. In the study group(n=30), 22 patients had low VLPP (

Key words:
female urinary incontinence, maximum urethral closure pressure, Valsalva leak-pointpressure