The Presence of Microorganisms in the Granulomatous Tissue of Chronic Periapical Lesions
Authors:
J. Kováč; D. Kováč
Authors‘ workplace:
Klinika stomatológie a maxilofaciálnej chirurgie LF UKo a OÚSA, Bratislava, SR
Published in:
Česká stomatologie / Praktické zubní lékařství, ročník 111, 2011, 6, s. 160-166
Category:
Review Article
Overview
Apical periodontitis is a sequel to endodontic infection and manifests itself as the host defense response to microbial challenge emanating from the root canal system to the periapical tissue. It is viewed as a dynamic encounter between microbial factors and host defenses at the interface between infected radicular pulp and periodontal ligament that results in local inflammation, resorption of hard tissues, destruction of other periapical tissues, and eventual formation of various histopathological categories of apical periodontitis, commonly referred to as periapical lesions. In the case of chronic periodontitis, proliferating epithelium can build a barrier at the root apex, preventing pulpal microorganisms from spreading out into the alveolar bone. The purpose of this article is to provide an overview of the literature relating to the presence of microorganisms in the granulomatous tissue of chronic periapical lesions.
Key words:
apical periodontitis – periapical lesions – periapical granuloma – granulomatous tissue – microorganisms
Sources
1. Barnett, F., Stevens, R., Tronstad, L.: Demonstration of Bacteroides Intermedius in periapical tissue using Indirect Immunofluorescence microscopy. Endod. Dent. Traumatol., roč. 6, 1990, č. 4, s. 153–156.
2. Garcia, C. C., Sempere, F. V., Diago, M. P., Bowen, E. M.: The post-endodontic periapical lesion: histologic and etiopathogenic aspects. Med. Oral. Patol. Oral. Cir. Bucal., roč. 12, 2007, č. 8, s. E585–590.
3. Hama, S., Takeichi, O., Hayashi, M., Komiyama, K., Ito, K.: Co-production of vascular endothelial cadherin and inducible nitric oxide synthase by endothelial cells in periapical granuloma. Int. Endod. J., roč. 39, 2006, č. 3, s. 179–184.
4. Hedman, W. J.: An investigation into residual periapical infection after pulp canal therapy. Oral. Surg. Oral. Med. Oral. Pathol., roč. 4, 1951, č. 9, s. 1173–1179.
5. Iwu, C., MacFarlane, T. W., MacKenzie, D., Stenhouse, D.: The microbiology of periapical granulomas. Oral. Surg. Oral. Med. Oral. Pathol., roč. 69, 1990, č. 4, s. 502–505.
6. Kováč, J.: Reakcia apikálneho parodontu na obsah koreňového kanálika zuba. Doktorandská dizertačná práca. Lekárska fakulta Univerzity Komenského, Bratislava 2010, 151 s.
7. Kováč, J., Kováč, D.: Imunitné procesy organizmu prebiehajúce pri apikálnej parodontitíde. Stomatológ, roč. 19, 2009, č. 1, s. 3–10.
8. Langeland, K., Block, R. M., Grossman, L. I.: A histopathologic and histobacteriologic study of 35 periapical endodontic surgical specimens. J. Endod., roč. 3, 1977, č. 1, s. 8–23.
9. Liapatas, S., Nakou, M., Rontogianni, D.: Inflammatory infiltrate of chronic periradicular lesions: an immunohistochemical study. Int. Endod. J., roč. 36, 2003, č. 7, s. 464–471.
10. Márton, I. J., Kiss, C.: Characterization of inflammatory cell infiltrate in dental periapical lesions. Int. Endod. J., roč. 26, 1993, č. 2, s. 131–136.
11. Márton, I. J., Balla, G., Hegedüs, C., Redl, P., Szilágyi, Z., Karmazsin, L.: The role of reactive oxygen intermediates in the pathogenesis of chronic apical periodontitis. Oral. Microbiol. Immunol., roč. 8, 1993, č. 4, s. 254–257.
12. Mazánek, J., Urban, F., a kol.: Stomatologické repetitorium. Grada Publishing, Praha 2003, 456 s.
13. Nair, P. N. R.: Apical periodontitis: a dynamic encounter between root canal infection and host response. Periodontol., 2000, roč. 13, 1997, s. 121–148.
14. Nair, P. N. R.: Light and electron microscopic studies of root canal flora and periapical lesions. J. Endod., roč. 13, 1987, č. 1, s. 29–39.
15. Nair, P. N. R.: Non-microbial etiology: foreign body reaction maintaining post-treatment apical periodontitis. Endod. Top., roč. 6, 2003, č. 1, s. 114–134.
16. Nair, P. N. R.: Non-microbial etiology: periapical cysts sustain post-treatment apical periodontitis. Endod. Top., roč. 6, 2003, č. 1, s. 96–113.
17. Nair, P. N. R.: On the causes of persistent apical periodontitis: a review. Int. Endod. J., roč. 39, 2006, č. 4, s. 249–281.
18. Nair, P. N. R.: Pathogenesis of apical periodontitis and the causes of endodontic failures. Crit. Rev. Oral. Biol. Med., roč. 15, 2004, č. 6, s. 348–381.
19. Nair, P. N. R., Pajarola, G., Schroeder, H. E.: Types and incidence of human periapical lesions obtained with extracted teeth. Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod., roč. 81, 1996, č. 1, s. 93–102.
20. Nair, P. N. R., Sjögren, U., Figdor, D., Sundqvist, G.: Persistent periapical radiolucencies of root filled human teeth, failed endodontic treatments and periapical scars. Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod., roč. 87, 1999, č. 5, s. 617–627.
21. Nair, P. N. R., Sjögren, U., Kahnberg, K. E., Krey, G., Sundqvist, G.: Intraradicular bacteria and fungi in root-filled, asymptomatic human teeth with therapy-resistant periapical lesions: a long-term light and electron microscopic follow-up study. J. Endod., roč. 16, 1990, č. 12, s. 580–588.
22. Nair, P. N. R., Sjögren, U., Schumacher, E., Sundqvist, G.: Radicular cyst affecting a root-filled human tooth: a long-term post-treatment follow-up. Int. Endod. J., roč. 26, 1993, č. 4, s. 225–233.
23. Ricucci, D., Mannocci, F., Ford, T. R.: A study of periapical lesions correlating the presence of a radiopaque lamina with histological findings. Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod., roč. 101, 2006, č. 3, s. 389–394.
24. Ricucci, D., Pascon, E. A., Pitt Ford, T. R., Langeland, K.: Epithelium and bacteria in periapical lesions. Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod., roč. 101, 2006, č. 2, s. 239–249.
25. Shindell, E.: A study of some periapical roentgenolucencies and their significance. Oral. Surg. Oral. Med. Oral. Pathol., roč. 14, 1961, č. 9, s. 1057–1065.
26. Siqueira Jr., J. F., Rôças, I. N.: Polymerase chain reaction-based analysis of microorganisms associated with failed endodontic treatment. Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod., roč. 97, 2004, č. 1, s. 85–94.
27. Slots, J., Sabeti, M., Simon, J. H.: Herpes virus in periapical pathosis: an etiopathologic relationship? Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod., roč. 96, 2003, č. 3, s. 327–331.
28. Stewart, G. G.: A study of bacteria found in root canals of anterior teeth and the probable ingress. J. Endod., roč. 2, 1947, č. 3, s. 8–11.
29. Tronstad, L., Sunde, P. T.: The evolving new understanding of endodontic infections. Endod. Top., roč. 6, 2003, č. 1, s. 57–77.
30. Wayman, B. E., Murata, S. M., Almeida, R. J., Fowler, C. B.: A bacteriological and histological evaluation of 58 periapical lesions. J. Endod., roč. 18, 1992, č. 4, s. 152–155.
31. Winkler, T. F. III, Mitchell, D. F., Healey, H. J.: A bacterial study of human periapical pathosis employing a modified gram tissue stain. Oral. Surg. Oral. Med. Oral. Pathol., roč. 34, 1972, č. 1, s. 109–116.
Labels
Maxillofacial surgery Orthodontics Dental medicineArticle was published in
Czech Dental Journal
2011 Issue 6
Most read in this issue
- The Presence of Microorganisms in the Granulomatous Tissue of Chronic Periapical Lesions
- Skeletal Age in Orthodontics
- Cephalometric Norms of Czech Population Sample
- The Occurrence of Anomalies of the Permanent Maxillary Lateral Incisors in Patients with Ectopically Erupting Permanent Canines