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Electroconvul-sive Treatment and Concurrent Treatment with Psychopharmaceutical Pre-parations: Efficacy of Combination


Authors: M. Hrdlička;  M. Blatný *;  M. Moráň **;  I. Maňasová ***
Authors‘ workplace: Dětská psychiatrická klinika 2. LF UK a FNM, Praha, zast. přednosta MUDr. M. Hrdlička, CSc. Psychologický ústav AV ČR, Brno, ředitelka PhDr L. Osecká, CSc. *Neurologická klinika LF MU a FNsP Bohunice, Brno, přednosta doc. MUDr. Z. Kadaňka, CSc. **Psychiat ***
Published in: Čes. a slov. Psychiat., , 1999, No. 4, pp. 201-211.
Category:

Overview

The presented retrospective study was made in female patients in the admis-sion department of a mental hospital. Electroconvulsive treatment was givenin all instances bilaterally, by short-pulse stimulation using a Thymaron ap-paratus. The group included a total of 99 patients, mean age 47.38 ± 15.74years (range 17 - 82) with diagnoses of unipolar and bipolar depression,mania, schizoaffective disorder and schizophrenia. The total number of ap-plied electroconvulsions (EC) was 663, the mean number per patient was 6.69± 2.24 (range 3 - 13 EC). The total number of electroconvulsions which couldbe evaluated was 657. After treatment the group included 77.7 % major res-ponders. The authors investigated the relationship of the class of pharmacot-herapeutic preparation (antidepressant, neuroleptic and benzodiazepines)and the therapeutic effect of electroconvulsive therapy. They found that ben-zodiazepines correlated significantly inversely with the improvement of CGIduring treatment (p = 0.021). The use of antidepressants and neuroleptics did not correlate significantly with the rate of onset of the first improvement norwith the total number of administered electroconvulsions.

Key words:
electroconvulsive therapy, therapeutic effect, psychophar-maceutical preparations, antidepressants, neuroleptics, benzodiazepines.

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Labels
Addictology Paediatric psychiatry Psychiatry
Topics Journals
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