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Simultaneous Determination of Dioxopromethazine and Phenylephrine in Eye DropsUsing Capillary Isotachophoresis


Authors: P. Kubačák;  I. Valášková;  Emil Havránek
Authors‘ workplace: Katedra farmaceutickej analýzy a nukleárnej farmácie Farmaceutickej fakulty Univerzity Komenského, Bratislava
Published in: Čes. slov. Farm., 2004; , 89-92
Category:

Overview

Dioxopromethazine and phenylephrine were determined simultaneously in eye drops using themethod of capillary isotachophoresis. Two elektrolyte systems with different compositions and pHwere examinated. Prior to analysis, the eye drops are diluted with water in a ratio 1:50. Precision,correctness, linearity, robustness, and selectivity of the ITP method were evaluated for bothelectrolyte sytems.

Key words:
isotachophoresis – dioxopromethazine – phenylephrine – eye drops – validation

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Labels
Pharmacy Clinical pharmacology

Article was published in

Czech and Slovak Pharmacy


2004 Issue 2

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