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Selection of the Extraction Agent and the Elaboration of the Technology of the Productionof an Extract with a Sedative Effect


Authors: A. Savickas;  K. Ramanauskiene;  N. Savickiene 1;  S. Kazlauskas 2;  R. Masteiková 3;  Z. Chalupová 3
Authors‘ workplace: Katedra technologie léků a OF Farmaceutické fakulty Kaunasské univerzity medicíny, Kaunas, Litevská republika 1Katedra farmaceutické chemie a farmakognozie Farmaceutické fakulty Kaunasské univerzity medicíny, Kaunas, Litevská republika2Katedra analytické
Published in: Čes. slov. Farm., 2004; , 35-38
Category:

Overview

The drugsValerinae radix, Crataegi fructus,Leonuri herba and Melissae folium were used to producea liquid plant extract. The experiment revealed that the extraction with 70% ethanol achieved thehighest concentration of extractable active principles. The optimal conditions for obtaining a sedativeextract are established when the method of repercolation is used, and in the production itselfthe batch of the drug is divided into equally large doses and a pre-prepared mixture of plant drugsis extracted. The extract prepared by this manner remains stable for the whole period of storage,i.e., 24 months.

Key words:
Valerianae radix – Crataegi fructus – Leonuri herba – Melissae folium – plant extract

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