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Advances in the Development of New Antituberculotics from the Group of Ortho-Condensed Heterocyclic CompoundsPart 3. Compounds Containing More Sorts of Heteroatoms in the Six-Membered Ring


Authors: K. Waisser;  O. Bureš;  P. Holý
Authors‘ workplace: Katedra anorganické a organické chemie Farmaceutické fakulty Univerzity Karlovy, Hradec Králové
Published in: Čes. slov. Farm., 2001; , 267-273
Category:

Overview

Tuberculosis and other mycobacterial diseases are considered to be one of the most importantproblems of contemporary health service. Since 1985 and particularly in the 1990s and at presentthe search for new structures of antimycobacterial agents have ranked among the foremost areasof chemotherapeutic research. The present review paper is already the 18 th communication ina group of review papers about substances with antituberculotic effects, and the third, final,communication devoted in this series about the development of new antimycobacterial agents toortho-condensed heterocyclic compounds in recent 15 years. The classification of ortho-condensedcompounds is based on six-membered heterocyclic substructural fragments and the present studydeals with the substructural fragments containing a greater number of different heteroatoms. Theliterature search is based on the journal Chemical Abstracts, Current Awareness in Biomedicine,part Mycobacteria, and original papers. Current Awareness in Biomedicine is, however, a veryimperfect literature search source, recording only a fraction of communications. Review papersabout five-membered heterocyclic antituberculotic ortho-condensed compounds was published inthe present journal in 1999.

Key words:
tuberculostatics – heterocycles – mycobacteria

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Labels
Pharmacy Clinical pharmacology

Article was published in

Czech and Slovak Pharmacy


2001 Issue 6

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