Haemangiomas are Common Benign Tumors of the Child
Authors:
K. Pramuková 1; R. Autrata 1; R. Faberová 2
Authors‘ workplace:
Dětská oční klinika, FN Brno
1; Pediatrická klinika, kožní oddělení, FN Brno
2
Published in:
Čes. a slov. Oftal., 72, 2016, No. 4, p. 138-148
Category:
Original Article
Overview
The paper presents summary report which approaching the issue of this affection and includes a retrospective study aims to evaluate the effectiveness and safety of treatment modalitiesinfantilehemangiomasperiorbitalandorbitallocalizationin paediatric patients observed in the period 2009–2014 on the Children’s Eye Clinic.
Key words:
haemangiom, treatment modalities
Sources
1. Al Buainian,H., Verhaeghe, E., Dierckxsens, L., Naeyaert, J.M.: Early treatment of hemangiomas with lasers. A review. Dermatology 2003;206(4):370–373.
2. Antaya, R.J.: Capillary malformation /online/./ cit. 25. 9. 2009/ Dostupné z: http://emedicine.medscape.com/article/1084479.
3. Antaya, R.J.: Infantile hemangioma /online/./cit. 29. 12. 2010/ Dostupné z: http://emedicine.medscape.com/article/1083849.
4. Autrata R. a kol.: Dětská oftalmologie. I. část. Sborník prací lékařské fakulty Masarykovy univerzity č. 122. 1. vyd. Masarykova univerzita, Brno, 2008, 137: s. 15-41.
5. Awadein, A., Fakhry, M.A.: Evaluation of intralesional propranolol for periocular capillary hemangioma. Clin Ophthalmol, 2011; 5: 000-000.DOPLNIT!
6. Bang, G.M., Setabutr, P: Periocular capillary hemangiomas: Indications and options for treatment. Middle East Afr J Ophtalmol,17, 2010; 2: 121–128.
7. Barnés, C.M., Huang, S., Kaipainen A., Sanoudou, D., Chen, E.J., Eichler, G.S, et al.: Evidence bz molecular profiling for a placental origin of infantile hemangioma. Proc Natl Acad Sci USA, 2005; 102: 19097–19102.
8. Bennet, M.L, Fleischer Jr, A.B., Champlin, S.L., Frieden, I.J.: Oral corticosteroid use is effective for cutaneous hemangiomas: an evidence-based evaluation: Arch Dermatol, 2001; 137: 1208–1213.
9. Boscolo, E., Bischoff, J.: Vasculogenesis in infantile hemangioma. Angiogenesis, 2009;12: 197–207.
10. Browning,, J., Frieden , I., Baselga, E. et al.: Congenital, Self- regressing Tufted Angioma. Arch Dermatol, 142, 2006; 6: 749–751.
11. Buckmiller, L.M, Munson, P.D:, Dyamenahalli, U., Dai, Y, Richter, G.T.: Propranolol for infantile hemangiomas: Early experience at tertiary vascular anomalies centre. The Laryngoskope, 120, 2010; 4: 676–681.
12. Burns,A.J., Navarro, J.A., Cooner, R.D.: Classification of vascular anomalies and the comprehensive treatment of hemangiomas. Plastic and Reconstructive Surgery, 124, 2009; 1S: 69–81.
13. Cogen, M., Elsas F.: Eyelid depigmentation following corticosteroid injection for infantile ocular adnexal hemangioma. J Pediatr Ophthalmol Strabismus, 1989; 26: 35–8.
14. Cruz ,O.A., Zarnegan ,S.R., Myers ,S.E.: Treatment of periocular capillary haemangioma with topical clobetasol proprionate. Ophthalmology, 1995; 102: 2012–2015.
15. Drolet, B.A, Esterly, N.B., Frieden, I.J.: Hemangiomas in children. N Engl J Med, 341, 1999; 3; 173–181.
16. Drolet, B.A, Swanson, E.A.: Hemangioma investigator group. Infantile hemangiomas: an emerging health issue link end to an increased rate of low birth weight infants. J Pediatr, 2008; 153: 712–715.
17. Droste, P., Ellis, F., Sondhi, N., Helveston, E.: Linear subcutaneous fat atrophy after corticosteroid injection of periocular hemangiomas. Am J Ophthalmol, 1988; 105: 65–69.
18. Dubois J, Garel L, David M, Powell J.: Vascular soft tissue tumors in infancy: distinguishing features on Doppler sonography. AJR Am J Roentgenol, 2002; 178: 1541–1545.
19. Elsas, F.J., Lewis, A.R.: Topical treatment of periocular capillary haemangioma. J Pediatr Ophthalmol Strabismus, 1994; 31:153–156.
20. Enjolras, O., Brevière, G.M., Roger, G., Tovi, M., Pellegrino , B., Varotti, E. et al.: Vincristine treatment for function- and life-threatening infancy hemangioma. Arch Pediatr 2004;11(2):99–107.
21. Faberová, R., Bučková, H., Procházka, J. a kol.: Nové poznatky léčby hemangiomů u dětí, jejich diferenciální diagnostika. Dermatologie pro praxi, 3, 2009, 2: 75–77.
22. Fabian, I.D, Ben-Zion, I., Samuel. C., Spierer, A.: Reduction in astigmatism using propranolol as first-line therapy for periocular capillary hemangioma. Am J Ophthalmol, 2011; 151(1): 53–58.
23. Fay, A., Nguyen, J., Jakobiec, F.A, Meyer-Junghaenel,L., Waner M.: Propranolol for isolated orbital infantile hemangioma. Arch Ophthalmol, 2010; 128(2): 256–258.
24. Frieden, I.J., Eichenfield, L.F:, Esterly, N.B., Geronemus, R., Mallory, S.B.: Guidelines of care for hemangiomas of infancy: American Academy of Dermatology guidelines/outcomes committee. J Am Acad Dermatol, 1997; 37: 631–637.
25. Frieden, I.J., Haggstrom, A.N, Drolet, B.A, Mancini, A.J., Friedlander S.F, Boon, L. et al.: Infantile hemangiomas: current knowledge, future directions. Proceedings of a research workshop on infantile hemangiomas, April 7.-9. 2005, Bethesda, Maryland, USA, Pediatric Dermatology, 22,2005; 5: 383–406.
26. Fuchsmann, C., Quintal, M.C., Ginguere, CH. et al.: Propranolol as First-line Treatment of Head and Neck Hemangiomas. Arch Otolaryngol Head Neck Surg, 137, 2011; 5: 471–478.
27. Gan, L.Q., Ni, S.L, Tan, Q., Wang, H.: A retrospective study of propranolol therapy in 109 infants with infantile hemangioma. Pediatr Dermatol, 2013; 30: 270–272.
28. Gladstone, G.J., Beckman, H.: Argon laser treatment of an eyelid margin capillary hemangioma. Ophthalmic Surg, 1983;14(11): 944–946.
29. Goldman, M.P: Tufted Angioma/online/./cit. 2. 10. 2009/ Dostupné z: http://emedicine.medscape.com/article/1086612.
30. Good, W.V., Hou, CH., Frieden, I.J: et al.: Evidence for Visual Compromise in Preverbal Children with Orbital Vascular Birthmarks. Am J Ophtalmol, 147, 2009; 4: 679–682.
31. Greene, A.K., Couto, R.A.: Oral prednisolone for infantile hemangioma: efficacy and safety using a standardized treatment protocol. Plast Reconstr Surg, 2011; 128: 743–752.
32. Greene, A.K.: Systemic corticosteroid is effective and safe treatment for problematic infantile hemangioma. Pediatr Dermatol 2010; 27: 322–323.
33. Greenberger, S., Adini, I., Boscolo, E., Mulliken, J.B., Bischoff, J.: Targeting NF-kB in infantile hemangioma-derived cells reduced VEGF-A expression. Angiogenesis 2010; 13: 327–335.
34. Greenberger, S., Boscolo, E., Adini, I., Mulliken, J.B., Bischoff, J.: Corticosteroid suppression of VEGF-A in infantile hemangioma-derived stem cells. N Engl J Med, 2010; 362: 1005–1013.
35. Guo, S., Ni N.: Topical treatment for capillary hemangioma of the eyelid using beta-blocker solution. Arch Ophthalmol, 2010; 128(2): 255–256.
36. Haggstrom, A.N., Drolet ,B.A., Baselga, E., Champlin, S.L., Garyon , M.C., Horii, K.A., et al.: Prospective study of infantile hemangiomas: clinical characteristics predicting complications and treatment. Pediatrics, 2006; 118: 882–887.
37. Haider, K.M., Plager, D.A, Neely, D.E, Eikenberry, J., Haggstrom A.: Outpatient treatment of periocular infantile hemangiomas with oral propranolol. J AAPOS 2010;14(3): 251–256.
38. Haik, B.G., Jakobiec, F.A., Ellsworth, R.M., Jones, I.S.: Capillary hemangioma of the lids and orbit: an analysis of the clinical features and therapeutic results in 101 cases. Ophtalmology, 1979; 86: 760–792.
39. Hemangioma investigator group Haggstrom, A.N., Drolet, B.A, Baselga, S.L., Chamli, S.L., Garzon, M.C. et al.: Prospective study of infantile hemangiomas: demographic, prenatal, and perinatal characteristics. J Pediatr, 2007;150: 291–294.
40. Hogeling, M., Adams, S., Wargon, O.: A Randomized Controlled Trial of Propranolol for Infantile Hemangiomas. Pediatrics, 128, 2011; 2: 259–266.
41. Hohenleutner, S., Badur-Ganter, E., Landthaler, M., Hohenleutner, U.: Long-term results in the treatment of childhood hemangioma with the flash lamp-pumped pulsed dye laser: an evaluation of 617 cases. Lasers Surg Med, 2001; 28(3): 273–277.
42. Holmes, W. J. M., Mishra, A., Gorst, C., Liew, S.H.: Propranolol as first-line treatment for infantile hemangiomas. Plastic and Reconstructive Surgery, 125, 2010; 1: 420–421.
43. Holland, K.E., Drolet, B.A.: Infantile hemangioma. Pediatr Clin North Am 2010; 57: 1069–1083.
44. Chakkittakandiyil, A., Phillips, R., Frieden, I.J. et al.: Timolol maleate 0.5% or 0.1% gel-forming solution for infantile hemangiomas: a retrospective, multicenter cohort study. Pediatr Dermatol, 2012; 29: 28–31.
45. Chang, L.C., Heggstrom, A.N., Drolet, B.A., Baselga, E., Champlin, S.L. et al.: Hemangioma investigator group. Growth Characteristics of infantile hemangiomas: implications for management. Pediatrics, 2008; 122: 360–367.
46. Chiller, K.G., Pasaro, D., Frieden, I.J.: Hemangiomas of infancy: clinical characteristics, morphologic subtypes, and relationship to race, ethnity, and sex. Arch Dermatol, 2002; 138: 1567–1576.
47. Itinteang, T., Tan, S.T., Brasch, H., Day, D.J.: Haemagenic endothelium in infantile haemangioma. J Clin Pathol, 2010; 63: 982–986.
48. Jacobs, AH.: Strawberry hemangiomas: the natural history of the untreated lesion. Calif Med, 1957; 86: 8–10.
49. Janmohamed SR, Madern GC, Nieuwenhuis K, de Laat PC, Oranje AP.: Evaluation of intra-lesional corticosteroids in the treatment of peri-ocular haemangioma of infancy: still an alternative besides propranolol. Pediatr Surg Int, 2012; 28: 393–398.
50. Jinnin., M, Ishihara, T., Boye, E., Olsen, BR.: Recent progress in studies of infantile hemangioma. J Dermatol, 2010; 37: 939–955.
51. Kanski, J.J. et al.: Clinical Ophthalmology a Systematic Approach. Fifth edition. Butterworth-Heinemann International Edition, London, 2003, 733 p.
52. Kasabach, H.H, Merritt, K.K.: Capillary hemangioma with extensive purpura report of a case. Am J Dis Child, 1940; 59: 1063.
53. Katz, H.P.: Thrombocytopenia associated with hemangioma: critical analysis of steroid therapy. In XI international congress of pediatrics, Tokyo;1965, p. 336–337.
54. Khan, Z.A., Boscolo, E., Picard, A., Psutka, S., Melero-Martin, J.M., Bartch, T.C. et al.: Multipotencial stem cells recapitulate human infantile hemangioma in immunodeficient mice. J Clin Invest, 2008; 118: 2592–2599.
55. Kilcline, C., Frieden, IJ.: Infantile hemangiomas: how common are they? A systematic review of the medical literature. Pediatr Dermatol, 2008; 25: 168–173.
56. Krafchik, B.R.: Kasabach-Meritt Syndrome /online/-/cit. 22. 2. 2010/ Dostupné z: http://emedicine.medscape.com/article/202455.
57. Kuchyňka, P. a kol.: Oční lékařství. 1. vydání. Grada, Praha, 2007, 768 s.
58. Kullbersh, J., Hochman, M.: Serial excision of facial hemangiomas. Arch Facial Plast Surg, 2011; 13(3): 199–202.
59. Kushner B, Lemke B.: Bilateral retinal embolization associated with intralesional corticosteroid injection for capillary hemangioma of infancy. J Pediatr Ophthalmol Strabismus, 1993; 30: 397–399.
60. Laubach, H.J., Anderson, R.R, Luger, T., Manstein, D.: Fractional photothermolysis for involuted infantile hemangioma. Arch Dermatol, 2009;145(7):748–750.
61. Leon-Villapalos, J., Wolfe, K., Kangesu, L.: GLUT-1.: an extra diagnostic tool to differentiate between haemangiomas and vascular malfomations. Br J Plast Surg, 2005; 58: 348–352.
62. Léauté - Labrèze, C., Dumas de la Roque, E., Hubiche, T., Borolevi, F., Thambo, J-B, Taïeb, A.: Propranolol for severe hemangiomas of infancy. N Engl J MED, 358, 2008; 24: 2649–2651.
63. Léuté-Labrèze, C., Taïeb, A.: Efficacy of beta-blockers in infantile capillary haemangiomas: the physiopathological significance and therapeutic consequences. Ann Dermatol Venereol, 2008; 135: 860–862.
64. Lister, WA.: The natural history of strawberry naevi. Lancet, 1938; 1: 1429–1434.
65. Marqueling, A.L., Oza, V., Frieden, I.J., Puttgen, K.B.: Propranolol and infantile hemangiomas four years later: a systematic review. Pediatr Dermatol, 2013; 30: 182–91.
66. Margileth, A.M., Museles, M.: Cutaneus hemangiomas in children. Diagnosis and conservative managment. JAMA 1965; 194: 523–526
67. Missoi, T.G, Lueder, G.T, Gilbertson, K., Bayliss, S.J.: Oral propranolol for treatment of periocular infantile hemangiomas. Arch Ophthalmol, 2011; 129(7): 899–903.
68. Miřejovský, P., Bednář, B. a kol.: Obecná patologie. Karolinum, Praha, 2002, 83 s.
69. Morrell, A.J., Willshaw, H.E.: Normalisation of refractive error after steroid injection for adnexal haemangiomas. Br J Ophthalmol, 1991; 75: 301–305.
70. Moukaddam, H., Pollak, J., Haims, A.H.: MRI characteristics and classification of peripheral vascular malformations and tumors. Skeletal Radio, 2009; 38: 535–547.
71. Mulliken, J.B., Glowacki J.: Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics. Plast Reconstr Surg, 1982; 69: 412–422.
72. Ni, N., Langer, P., Wagner, R., Guo S.: Topical timolol for periocular hemangioma: report of further study. Arch Ophthalmol, 2011; 129(3): 377–379.
73. North, P.E., Waner, M., Mizeracki, A., Mrak, R.E, Nicholas, R., Kincannon, J., et al.: A unique microvascular phenotype shared by juvenile hemangiomas and human placenta. Arch Dermatol, 2001; 137: 559–570.
74. Otradovec, J: a kol.: Klinická neurooftalmologie. 1. vydání. Grada, Praha, 2003, 487 s.
75. Pasyk KA, Grabb WC, Cherry GW.: Cellular haemangioma. Light and electron microscopic studies of two cases. Virchows Arch A Pathol Anat Histol, 1982; 396: 103–126.
76. Pierson, J.C.: Dermatologic Manifestations of Pyogenic Granuloma (Lobular Capillary hemangioma)/online/./cit. 29. 04. 2010/ Dostupnéz:http://emedicine medscape.com/article/1084701.
77. Povýšil, C. a kol.: Speciální patologie I. díl. Karolinum, Praha, 2001, 98 s.
78. Prasetyono, T.O., Djoenaedi, I.: Efficacy of intralesional steroid injection in head and neck hemangioma: a systematic review. Ann Plast Surg, 2011; 66: 98–106.
79. Press, U.P.: Sensationelle Zufallsentdeckung. Ophtalmologische nachrichten. Sonderteil zum 23. DOC – kongress, 2010; 10: 41–42.
80. Price, C. J., Latttouf, C., Baum, B. et al.: Propranolol vs Corticosteroids for Infantile Hemangiomas /online/./ cit. 15. 8. 2011/ Dostupné z http://archderm.ama-assn.org/cgi/content/full/archdermatol.2011.203.
81. Przewratil, P., Sitkiewicz, A., Wyka, K., Andrzejewska, E.: Serum levels of vascular endothelial growth factor and basic fibroblastic growth factor in children with hemangiomas and vascular malformations – preliminary report. Pediatr Dermatol, 2009; 26: 399–404.
82. Ranchod, T.M., Frieden, I.J., Fredrick D.R.: Corticosteroid treatment of periorbital haemangioma of infancy: a review of the evidence. Br J Ophthalmol 2005; 89: 1134-1138.
83. Robb, R.M.: Refractive errors associated with hemangiomas of the eyelids and orbit in infancy.Am j Ophtalmol 1977; 83: 52-58.
84. Ruttum, M.S., Abrams, G.W., Harris, G.J., Ellis, M.K.: Bilateral retinal embolization associated with intralesional corticosteroid injection for capillary hemangioma of infancy. J Pediatr Ophthalmol Strabismus 1993; 30: 4–7.
85. Sans V, de la Roque ED, Berge J, Grenier N, Boralevi F, Mazereeuw-Hautier J, Lipsker D, Dupuis E, Ezzedine K, Vergnes P, Taïeb A, Léauté-Labrèze C.: Propranolol for severe infantile hemangiomas: follow-up report. Pediatrics 2009; 124: e423–431.
86. Seiff, S.: Capillary Hemangioma/online/./ cit.29. 6. 2011/ Dostupné z: http://emedicine.medscape.com/article/1218805.
87. Shorr, N., Seiff, S.R.: Central retinal artery occlusion associated with periocular corticosteroid injection for juvenile hemangioma. Ophthalmic Surg, 1986; 17(4): 229–231.
88. Schwartz, SR., Blei., F., Ceisler, E., et al.: Risk factors for amblyopia in children with capillary hemangiomas of the eyelid and orbit. JAAPOS, 2006; 10: 262–268.
89. Smoller, B.R., Apfelberg, D.B.: Infantile (juvenile) capillary hemangioma: a tumor of heterogeneous cellular elements. J Cutan Pathol, 1993; 20: 330–6.
90. Sutula FC, Glover AT.: Eyelid necrosis following intralesional corticosteroid injection for capillary hemangioma. Ophthalmic Surg, 1987; 18: 103–105.
91. Taban, M., Goldberg, R.A.: Propranolol for orbital hemangioma. Ophthalmology, 2010;117(1): 195.
92. Takahashi, K., Mulliken, J.B., Kozakewich, H.P., Rogers, R.A., Folkman, J., Eyekowitz, R.A: Cellular markers taht distinguish the phases of hemangioma during infancy and childhood. J Clin Invest, 1994; 93: 2357–2364.
93. Thoumazet, F., Léauté-Labrèze, C., Colin, J., Mortemousque, B.: Efficacy of systemic propranolol for severe infantile haemangioma of the orbit and eyelid: a case study of eight patients. Br J Ophthalmol, 2012; 96: 370–374.
94. Vassallo, P., Forte, R., Di Mezza, A., Magli, A.: Treatment of infantile capillary hemangioma of the eyelid with systemic propranolol. Am J Ophthalmol, 2013; 155: 165–170.
95. Vasquez-Botet, R., Reyes, B.A., Vazquez-Botet, M.: Sclerodermiform linear atrophy after the use of intralesional steroids for periorbital hemangiomas: a review of complications. J Pediatr Ophthalmol Strabismus, 1989; 26: 124–127.
96. Walker, R.S, Custer, P.L, Nerad, J.A.: Surgical excision of periorbital capillary hemangiomas. Ophthalmology, 1994; 101(8): 1333–1340.
97. Weibel, L.: Propranolol – eine neue Therapie für infantile Hämangiome. Paediatrica, 20, 2009; 2: 27–29.
98. Weiss, A.H, Kelly, J.P.: Reappraisal of astigmatism induced by periocular capillary hemangioma and treatment with intralesional corticosteroids injection. Ophthalmology, 2008; 115(2): 390–397.
99. Zhang, L, Lin, X., Wang, W, Zhuang, X, Dong., J., Qi, Z. et al.: Circulating level of vascular endothelial growth factor in differentiating hemangioma from vascular malformation patients. Plast Reconst Surg, 2005; 116: 200–204.
100. Zheng, J.W., Zhang., L., Zhou, Q., Mai, H.M., Wang, Y.A., Fan, X.D., Qin, Z.P., Wang, X.K., Zhao, Y.F.: A practical guide to treatment of infantile hemangiomas of the haed and neck. Int J Clin Exp Med. 2013;6:851–860.
Labels
OphthalmologyArticle was published in
Czech and Slovak Ophthalmology
2016 Issue 4
Most read in this issue
- Gene Therapy for Inherited RETINAL AND OPTIC NERVE Disorders: Current Knowledge
- Haemangiomas are Common Benign Tumors of the Child
- New Diagnostic Imaging Technique – Shear Wave Elastography
- Ocular Motility Disorders with Diplopia Like the first Symptoms of Paranasal Tumours with Orbital Invasion – a Case Report