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Histopathological Picture after Chemical Injury, Role of Limbal Epithelial BasalCells


Authors: Kozák I. Trbolová A. Ševčíková Z. Ledecký V. Juhás T.
Authors‘ workplace: Očná klinika LF UPJŠ, Košice, prednosta doc. MUDr. T. Juhás, CSc., doc. MVDr. Ledecký V., CSc., Katedra patologickej anatómie UVL, Košice, vedúci katedry, prof. MVDr. M. Levkut, CSc.
Published in: Čes. a slov. Oftal., , 2001, No. 2, p. 104-108
Category:

Overview

The aim of this experimental study was to evaluate the role of limbal stem cellson corneal wound healing. The experimental objects were New Zealand whiterabbits. Damage to the cornea was caused by 2,5 N NaOH solution for 50 sec. andwas subsequently washed out by saline solution . The rabbits were euthanased 24hours after alkaly burn and the tissue was fixated in 10% formalin. The sampleswereembeddedinparaffin andstainedwithhaematoxilin andeosin. Thespecimenshowed focal inflammatory reaction with the presence of macrophages an round- nucleated cells in the limbal area.

Key words:
cornea, chemical burn, limbal cells

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