Refractory myasthenia gravis – clinical characteristics and possibilities of biological treatment

Czech version

Authors: J. Piťha ^1,2
Authors‘ workplace: Neurologická klinika 1. LF UK a VFN Praha ¹; MS Centrum Teplice, Neurologické oddělení, KZ a. s. – Nemocnice Teplice o. z. ²
Published in: Cesk Slov Neurol N 2019; 82(5): 490-495
Category: Review Article
doi: https://doi.org/10.14735/amcsnn2019490

Overview

Refractory myasthenia gravis, despite significant advances in the diagnosis and therapy of this autoimmune disease, is an important medical and socioeconomic problem. The article deals with the immunopathogenesis of myasthenia gravis, the characteristics of the disease, the clinical context in terms of risk groups of patients, the quantification of neurological deficits and the treatment options aimed at biological therapy.

The author declares he has no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.

Přijato k recenzi: 9. 5. 2019

Přijato do tisku: 13. 8. 2019

Keywords:

myasthenia gravis – MuSK – refractory form – clinical characteristics

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