Factors affecting early diagnosis of amyotrophic lateral sclerosis
Authors:
P. Matejička; M. Gažiová; M. Minár
Authors‘ workplace:
II. neurologická klinika LF UK a UN, Bratislava
Published in:
Cesk Slov Neurol N 2018; 81(3): 353-357
Category:
Short Communication
doi:
https://doi.org/10.14735/amcsnn2018353
Overview
Patients with amyotrophic lateral sclerosis (ALS) go to specialized neuromuscular centres during the advanced stages, when severe multiple muscle atrophies, dysphagia and respiratory insufficiency are present. Its insidious onset is the main reason. Various factors may play a role – caused either by physicians (wrong diagnostic approaches, obscure electromyography findings, wrong interpretation, etc.), or by patients (delayed decision to seek medical consultation). The aim of our study was to identify certain factors affecting the time from ALS symptom onset to its diagnosis.
Key words:
amyotrophic lateral sclerosis – diagnosis – electromyography – treatment
The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.
The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.
Sources
1. Hardiman O, Al-Chalabi A, Brayne C et al. The changing picture of amyotrophic lateral sclerosis: lessons from European registers. J Neurol Neurosurg Psychiatry 2017; 88(7): 557–563. doi: 10.1136/ jnnp-2016-314495.
2. Ambler Z. Amyotrofická laterální skleróza. Neurol praxi 2006; 7(1): 9–12.
3. Brooks BR, Miller RG, Swash M et al. El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 2000; 1(5): 293–299.
4. de Carvalho M, Dengler R, Eisen A et al. Electrodiag-nostic criteria for diagnosis of ALS. Clin Neurophysiol 2008; 119(3): 497–503. doi: 10.1016/ j.clinph.2007.09.143.
5. Vlčková E. Amyotrofická laterální skleróza. Neurol praxi 2016; 17(6): 362–365.
6. Miller RG, Mitchell JD, Moore DH. Riluzole for amyotrophic lateral sclerosis (ALS)/ motor neuron disease (MND). Cochrane Database of Syst Rev 2012; (3): CD001447. doi: 10.1002/ 14651858.CD001447.pub3.
7. Baumgartner D, Marusič P, Mazanec R. Kmenové buňky v léčbě amyotrofické laterální sklerózy – přehled současných klinických zkušeností. Cesk Slov Neurol N 2017; 80/ 113(1): 27–33. doi: 10.14735/ amcsnn201727.
8. Cellura E, Spataro R, Taiello AC et al. Factors affecting the diagnostic delay in amyotrophic lateral sclerosis. Clin Neurol Neurosurg 2012; 114(6): 550–554. doi: 10.1016/ j.clineuro.2011.11.026.
9. Wijesekera LC, Leigh PN. Amyotrophic lateral sclerosis. Orphanet J Rare Dis 2009; 4(1): 3. doi: 10.1186/ 1750-1172-4-3.
10. Wijesekera LC, Mathers S, Talman P et al. Natural history and clinical features of the flail arm and flail leg ALS variants. Neurology 2009; 72(12): 1087–1094. doi: 10.1212/ 01.wnl.0000345041.83406.a2.
11. Matoušek P, Zeleník K, Menšíková A et al. Náhle vzniklá dušnost jako příznak vedoucí k diagnóze amyotrofické laterální sklerózy – kazuistika. Cesk Slov Neurol N 2011; 74/ 107(2): 215–218.
12. Makkonen T, Korpijaakko-Huuhka AM, Ruottinen H et al. Oral motor functions, speech and communication before a definitive diagnosis of amyotrophic lateral sclerosis. J Commun Disord 2016; 61: 97–105. doi: 10.1016/ j.jcomdis.2016.04.002.
13. Murono S, Hamaguchi T, Yoshida H. Evaluation of dysphagia at the initial diagnosis of amyotrophic lateral sclerosis. Auris Nasus Larynx 2015; 42(3): 213–217. doi: 10.1016/ j.anl.2014.10.012.
14. Logroscino G, Traynor BJ, Hardiman O et al. Incidence of amyotrophic lateral sclerosis in Europe. J. Neurol Neurosurg Psychiatry 2010; 81(4): 385–390. doi: 10.1136/ jnnp.2009.183525.
Labels
Paediatric neurology Physiotherapist, university degree Neurosurgery Neurology Rehabilitation Pain managementArticle was published in
Czech and Slovak Neurology and Neurosurgery
2018 Issue 3
Most read in this issue
- Chronic inflammatory demyelinating polyradiculoneuropathy
- Factors affecting early diagnosis of amyotrophic lateral sclerosis
- Muscle biopsy in 10 key points
- Is essential tremor a disease or a syndrome?