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Premalignancies of Colon


Authors: M. Šachlová
Authors‘ workplace: Gastroenterologické oddělení, Masarykův onkologický ústav, Brno
Published in: Klin Onkol 2013; 26(Supplementum): 38-43

Overview

The most common premalignant lesions of colorectal carcinoma include sporadic adenomas. Tubular and tubulovillous adenomas with mild dysplasia are considered benign lesions, while villous adenomas represent tumors with uncertain bio­logical behavior. In recent years, demonstrable growth of flat lesions in the proximal intestine has been seen. Precision and yield of colonoscopy depends to some extent on good preparation, careful screening of intestine and use of new instruments of better quality. As an indicator of screening colonoscopy quality, the so‑ called adenoma detection rate is used. The text briefly describes options of endoscopic and surgical resolving of premalignancies. In the Czech Republic, attendance in the screening program is low, which could be changed by prepared addressed invitations of clients. The population with a genetic or familiar risk is examined according to recommended procedures intended for increased‑ risk persons.

Key words:
adenomatous polyp –  screening –  clinical practice

The author declares she has no potential conflicts of interest concerning drugs, pruducts, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.

Submitted:
26. 8. 2013

Accepted:
13. 10. 2013


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