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Acute myocardial infarction in women


Authors: T. Janota
Authors‘ workplace: III. interní klinika 1. LF a VFN v Praze
Published in: Kardiol Rev Int Med 2006, 8(4): 198-201
Category: Editorial

Overview

Acute myocardial infarction (AMI) is one of the most frequent causes of death in women as well as in men. However, thanks to the delaying effects of estrogens before menopause on atherosclerosis development AMI is most prevalent in higher age groups than in men. Women with AMI are therefore older and suffer from a wider range of comorbidities like hypertension, diabetes, hyperlipidaemias and heart failure. Frequently, AMI in women lacks the typical textbook signs and symptoms, and coronary artery spasm plays larger role in aetiology of AMI. Different vegetative responses in women predispose to more marked and more frequent vagotonic reaction with hypotension and bradycardia. Women also seek medical attention later in the course of the illness. They are treated with less invasive methods and with higher rate of complications. However, after adjusting for age, women show only higher early mortality, especially in-hospital and in younger women. Women profit less from surgical revascularisation. The effects of thrombolytic and angioplastic treatments are similar to men after adjusting for age and other variables.

Key words:
acute myocardial infarction - women


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