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SAA Consensus Statement EAS 2021: Triglyceride-rich lipoproteins and their remnant particles – a review of metabolism, role in atherosclerotic cardiovascular disease, and new therapeutic strategies


Authors: Branislav Vohnout;  Martin Čaprnda;  Ubomíra Fábryová;  Anna Hlavatá;  Michaela Kadurová;  Ján Lietava;  Daniel Pella;  Katarína Rašlová;  Jana Sirotiaková;  Jana Tisoňová;  Štefan Tóth
Published in: AtheroRev 2025; 10(1): 8-17
Category: Guidelines


Sources

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Das Pradhan A, Glynn RJ, Fruchart JC et al. Triglyceride lowering with pemafibrate to reduce cardiovascular risk. N Engl J Med 2022; 387(21): 1923–34. Dostupné z DOI: <http://dx.doi.org/10.1056/NEJMoa2210645>.

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Rubins HB, Robins SJ, Collins D et al. [Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group]. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. N Engl J Med 1999; 341(6): 410–418. Dostupné z DOI: <http://dx.doi.org/10.1056/NEJM199908053410604>.

Chait A, Eckel RH, Vrablik M et al. Lipid-lowering in diabetes: An update. Atheroscleros 2024; 394: 117313is. Dostupné z DOI: <http://dx.doi.org/10.1016/j.atherosclerosis.2023.117313>.

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Corpechot C, Chazouillères O, Rousseau A et al. A Placebo-Controlled Trial of Bezafibrate in Primary Biliary Cholangitis. N Engl J Med. 2018; 378(23): 2171–2181. Dostupné z DOI: <http://dx.doi.org/10.1056/NEJMoa1714519>.

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Keech AC, Mitchell P, Summanen PA et al. Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): a randomized controlled trial. Lancet 2007; 370(9600): 1687–1697. Dostupné z DOI: <http://dx.doi.org/10.1016/S0140–6736(07)61607–9>.

Preiss D, Logue J, Sammons E et al. Effect of Fenofibrate on Progression of Diabetic Retinopathy. NEJM Evid 2024; 3(8): EVIDoa2400179. Dostupné z DOI: <http://dx.doi.org/10.1056/EVIDoa2400179>.

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Angiology Diabetology Internal medicine Cardiology General practitioner for adults

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