GLP-1 receptor agonists: antidiabetic agents with antiatherogenic effect

Czech version

Authors: Ivan Tkáč
Authors‘ workplace: Excelentný tím pre výskum aterosklerózy (EXTASY), IV. interná klinika UPJŠ LF a UN LP Košice
Published in: AtheroRev 2020; 5(3): 181-184
Category: Clinical Studies

Overview

GLP-1 receptor agonists (GLP1 RA) have been used in the treatment of type 2 diabetes for the past 15 years. In the last five years, several randomized clinical trials with drugs of this group – liraglutide, semaglutide, albiglutide and dulaglutide – have demonstrated their ability to prevent major cardiovascular events. Therefore, some international recommendations list them as the drugs of the first choice in the treatment of patients with type 2 diabetes and proven clinical or subclinical atherosclerosis.

Keywords:

cardiovascular prevention – GLP-1 receptor agonists – treatment of type 2 diabetes

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