Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors

Czech version

Authors: Ján Murín
Authors‘ workplace: I. interná klinika LF UK a UN Bratislava, nemocnica Staré mesto
Published in: AtheroRev 2016; 1(3): 151-154
Category: Reviews

Overview

Cardiovascular diseases contribute in Slovakia with 53 % to all-cause mortality. These diseases have usually an atherogenic background and the development of these diseases is impossible without an increase in serum LDL-cholesterol. For prevention and treatment of these diseases we use a change of life style and statins, but now a new group of drug will enter this arena – PCSK9 inhibitors. Author presents essential data about mechanisms of effects of these new drugs, about short history of these drugs development and presents important clinical studies with these drugs. He tries to focus on patients who will benefit mostly from this treatment.

Key words:
atherosclerosis – cardiovascular diseases – LDL-cholesterol – PCSK9 inhibitors

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Labels

Angiology Diabetology Internal medicine Cardiology General practitioner for adults

Atherogenic dyslipidemia – a new target in cardiovascular prevention

Peripheral arterial disease (PAD) of lower extremity and dyslipidemia

Role of microRNAs in the pathophysiology of atherosclerosis and their potential clinical use

What other possibilities of reducing blood pressure we have, apart from antihypertensives

Arterin – a nutritional supplement in the treatment of dyslipidemia: results of a short-term clinical follow-up study

High prevalence of cardiovascular risk factors and inadequate control of LDL cholesterol levels in the population of 40-year old men and 50-year old women in the Czech Republic

Can we improve primary prevention of ischemic heart disease? Which way?

From dyslipidemia to ischemic heart disease and vice versa

Article was published in

Athero Review

2016 Issue 3