Year 2022 in Review – Intensive care medicine – Cardiovascular and general issues

Czech version

Authors: J. Kletečka ^1,2; J. Zatloukal ^1,2; O. Smékalová ^1,2,3; J. Beneš ^1,2,4
Authors‘ workplace: Klinika anesteziologie, resuscitace a intenzivní medicíny, Univerzita Karlova a Lékařská fakulta v Plzni ¹; Klinika anesteziologie, resuscitace a intenzivní medicíny, Fakultní nemocnice Plzeň ²; Ústav simulační medicíny, Lékařská fakulta Masarykovy univerzity Brno ³; Biomedicínské centrum, Univerzita Karlova a Lékařská fakulta v Plzni ⁴
Published in: Anest. intenziv. Med., 33, 2022, č. 6, s. 302-307
Category: Review Article

Overview

In 2022, intensive medicine all around the world gradually began to return to standard tracks, although we could still observe the effects of the pandemic waves of the disease COVID-19. In the literature, we could note the publication of research studies of “violently terminated” pandemics and new works. This review article presents a selection of the most interesting published articles in general intensive care medicine and those focusing on cardiovascular issues.

Keywords:

shock – infusion therapy – cardiovascular system – heart failure – prognostication – circulatory arrest – intensive care medicine

Sources

1. Kok B, Wolthuis D, Bosch F, van der Hoeven H, Blans M. POCUS in dyspnea, nontraumatic hypotension, and shock; a systematic review of existing evidence. Eur J Intern Med. 2022. https://doi.org/10.1016/j.ejim.2022. 07. 017.

2. Pallesen J, Bhavsar R, Fjølner J, Bakke SA, Krog J, Andersen MAS, et al. The effects of preoperative focused cardiac ultrasound in high‐risk patients: A randomised controlled trial (PREOPFOCUS). Acta Anaesthesiol Scand. 2022;66:1174-84. https://doi.org/10.1111/aas.14134.

3. Póvoa P, Martin‑Loeches I, Duska F, Hästbacka J, Gomes E, Le Roy A, et al. Updated competency‑based training in intensive care: next step towards a healthcare union in Europe? Intensive Care Med. 2022;48:1093-4. https://doi.org/10.1007/s00<134-022-06783-1.

4. Fage N, Demiselle J, Seegers V, Merdji H, Grelon F, Mégarbane B, et al. Effects of mean arterial pressure target on mottling and arterial lactate normalization in patients with septic shock: a post hoc analysis of the SEPSISPAM randomized trial. Ann Intensive Care. 2022;12:78. https://doi.org/10.1186/s13613-022-01053-1.

5. Raia L, Gabarre P, Bonny V, Urbina T, Missri L, Boelle P‑Y, et al. Kinetics of capillary refill time after fluid challenge. Ann Intensive Care. 2022;12:74. https://doi.org/10.1186/s13613- 022-01049-x.

6. Merdji H, Curtiaud A, Aheto A, Studer A, Harjola V‑P, Monnier A, et al. Performance of Early Capillary Refill Time Measurement on Outcomes in Cardiogenic Shock: An Observational, Prospective Multicentric Study. Am J Respir Crit Care Med. 2022. https://doi. org/10.1164/rccm.202204-0687OC.

7. Finfer S, Micallef S, Hammond N, Navarra L, Bellomo R, Billot L, et al. Balanced Multielectrolyte Solution versus Saline in Critically Ill Adults. N Engl J Med. 2022;386:815–26. https://doi.org/10.1056/NEJMoa2114464.

8. Hammond NE, Zampieri FG, Di Tanna GL, Garside T, Adigbli D, Cavalcanti AB, et al. Balanced Crystalloids versus Saline in Critically Ill Adults – A Systematic Review with Meta‑Analysis. NEJM Evid. 2022;1:1-12. https://doi.org/10.1056/EVIDoa2100010.

9. Nam JH, Kwack HJ, Ha WS, Chung J‑E. Resuscitation Fluids for Patients at High Risk of Multiple Organ Dysfunction Syndromes: A Systematic Review and Meta‑analysis. Korean J Clin Pharm. 2022;32:251-9. https://doi.org/10.24304/kjcp.2022. 32. 3.251.

10. Zampieri FG, Machado FR, Biondi RS, Freitas FGR, Veiga VC, Figueiredo RC, et al. Association between Type of Fluid Received Prior to Enrollment, Type of Admission, and Effect of Balanced Crystalloid in Critically Ill Adults: A Secondary Exploratory Analysis of the Ba- SICS Clinical Trial. Am J Respir Crit Care Med. 2022;205:1419-28. https://doi.org/10.1164/ rccm.202111-2484OC.

11. Lombardo S, Smith MC, Semler MW, Wang L, Dear ML, Lindsell CJ, et al. Balanced Crystalloid versus Saline in Adults with Traumatic Brain Injury: Secondary Analysis of a Clinical Trial. J Neurotrauma. 2022;39:1159-67. https://doi.org/10.1089/neu.2021.0465.

12. Dong W‑H, Yan W‑Q, Song X, Zhou W‑Q, Chen Z. Fluid resuscitation with balanced crystalloids versus normal saline in critically ill patients: a systematic review and meta‑analysis. Scand J Trauma Resusc Emerg Med. 2022;30:28. https://doi.org/10.1186/s13049-022-01015-3.

13. Meyhoff TS, Hjortrup PB, Wetterslev J, Sivapalan P, Laake JH, Cronhjort M, et al. Restriction of Intravenous Fluid in ICU Patients with Septic Shock. N Engl J Med. 2022;386:2459- 70. https://doi.org/10.1056/NEJMoa2202707.

14. Jessen MK, Andersen LW, Thomsen M‑LH, Kristensen P, Hayeri W, Hassel RE, et al. Restrictive fluids versus standard care in adults with sepsis in the emergency department (REFACED): A multicenter, randomized feasibility trial. Acad Emerg Med. 2022;29:1172-84. https:// doi.org/10.1111/acem.14546.

15. de‑Madaria E, Buxbaum JL, Maisonneuve P, García García de Paredes A, Zapater P, Guilabert L, et al. Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis. N Engl J Med. 2022;387:989-1000. https://doi.org/10.1056/NEJMoa2202884.

16. Mallat J, Fischer M‑O, Granier M, Vinsonneau C, Jonard M, Mahjoub Y, et al. Passive leg raising‑ induced changes in pulse pressure variation to assess fluid responsiveness in mechanically ventilated patients: a multicentre prospective observational study. Br J Anaesth. 2022;129:308-16. https://doi.org/10.1016/j.bja.2022. 04. 031.

17. Russell DW, Casey JD, Gibbs KW, Ghamande S, Dargin JM, Vonderhaar DJ, et al. Effect of Fluid Bolus Administration on Cardiovascular Collapse Among Critically Ill Patients Undergoing Tracheal Intubation. JAMA. 2022;328:270. https://doi.org/10.1001/jama.2022.9792.

18. Russotto V, Tassistro E, Myatra SN, Parotto M, Antolini L, Bauer P, et al. Peri‑ intubation Cardiovascular Collapse in Patients Who Are Critically Ill: Insights from the INTUBE Study. Am J Respir Crit Care Med. 2022;206:449-58. https://doi.org/10.1164/rccm.202111-2575OC.

19. Maiwall R, Kumar A, Pasupuleti SSR, Hidam AK, Tevethia H, Kumar G, et al. A randomized‑controlled trial comparing 20% albumin to plasmalyte in patients with cirrhosis and sepsis‑induced hypotension [ALPS trial]. J Hepatol. 2022;77:670-82. https://doi.org/10.1016/j. jhep.2022. 03. 043.

20. Pitre T, Kiflen M, Helmeczi W, Dionne JC, Rewa O, Bagshaw SM, et al. The Comparative Effectiveness of Vasoactive Treatments for Hepatorenal Syndrome: A Systematic Review and Network Meta‑Analysis*. Crit Care Med. 2022;50:1419-29. https://doi.org/10.1097/ CCM.0000000000005595.

21. Rashid Farokhi F, Kalateh E, Shafaghi S, Schneider AG, Mortazavi SM, Jamaati H, et al. Applying bio‑ impedance vector analysis (BIVA) to adjust ultrafiltration rate in critically ill patients on continuous renal replacement therapy: A randomized controlled trial. J Crit Care. 2022;72:154146. https://doi.org/10.1016/j.jcrc.2022.154146.

22. Mullens W, Dauw J, Martens P, Verbrugge FH, Nijst P, Meekers E, et al. Acetazolamide in Acute Decompensated Heart Failure with Volume Overload. N Engl J Med. 2022;387:1185- 95. https://doi.org/10.1056/NEJMoa2203094.

23. Sedhai YR, Shrestha DB, Budhathoki P, Memon W, Acharya R, Gaire S, et al. Vasopressin versus norepinephrine as the first‑line vasopressor in septic shock: A systematic review and meta‑analysis. J Clin Transl Res. 2022;8:185-99. https://doi.org/10.18053/jctres.08.202203.005.

24. Fernando SM, Mathew R, Sadeghirad B, Brodie D, Belley‑Côté EP, Thiele H, et al. Inotropes, vasopressors, and mechanical circulatory support for treatment of cardiogenic shock complicating myocardial infarction: a systematic review and network meta‑analysis. Can J Anaesth. 2022;77:999-1009. https://doi.org/10.1007/s12630-022-02337-7.

25. Zhao C‑C, Zhai Y‑J, Hu Z‑J, Huo Y, Li Z‑Q, Zhu G‑J. Efficacy and safety of methylene blue in patients with vasodilatory shock: A systematic review and meta‑analysis. Front Med. 2022;9. https://doi.org/10.3389/fmed.2022.950596.

26. Desebbe O, Rinehart J, Van der Linden P, Cannesson M, Delannoy B, Vigneron M, et al. Control of Postoperative Hypotension Using a Closed‑Loop System for Norepinephrine Infusion in Patients After Cardiac Surgery: A Randomized Trial. Anesth Analg. 2022;134:964- 73. https://doi.org/10.1213/ANE.0000000000005888.

27. Fernando SM, Mathew R, Sadeghirad B, Brodie D, Belley‑Côté EP, Thiele H, van Diepen S, Fan E, Di Santo P, Simard T, Russo JJ, Tran A, Lévy B, Combes A, Hibbert B, Rochwerg B. Inotropes, vasopressors, and mechanical circulatory support for treatment of cardiogenic shock complicating myocardial infarction: a systematic review and network meta‑analysis. Can J Anaesth. 2022 Dec;69(12):1537-1553. English. doi: 10.1007/s12630-022-02337-7. Epub 2022 Oct 4. PMID: 36195825.

28. Zhang Q, Han Y, Sun S, Zhang C, Liu H, Wang B, et al. Mortality in cardiogenic shock patients receiving mechanical circulatory support: a network meta‑analysis. BMC Cardiovasc Disord. 2022;22:48. https://doi.org/10.1186/s12872-022-02493-0.

29. Metra M, Chioncel O, Cotter G, Davison B, Filippatos G, Mebazaa A, et al. Safety and efficacy of istaroxime in patients with acute heart failure‐related pre‐cardiogenic shock – a multicentre, randomized, double‐blind, placebo‐controlled, parallel group study (<scp>- SEISMiC</scp>). Eur J Heart Fail. 2022. https://doi.org/10.1002/ejhf.2629.

30. Garside T, Bedford JP, Vollam S, Gerry S, Rajappan K, Watkinson PJ. Increased long‑term mortality following new‑onset atrial fibrillation in the intensive care unit: A systematic review and meta‑analysis. J Crit Care. 2022;72:154161. https://doi.org/10.1016/j.jcrc.2022.154161.

31. Søgaard M, Skjøth F, Nielsen PB, Smit J, Dalager‑Pedersen M, Larsen TB, et al. Thromboembolic Risk in Patients With Pneumonia and New‑Onset Atrial Fibrillation Not Receiving Anticoagulation Therapy. JAMA Netw Open. 2022;5:e2213945. https://doi.org/10.1001/jamanetworkopen. 2022.13945.

32. Yang BY, Bulger N, Chocron R, Counts CR, Drucker C, Yin L, et al. Analysis of Epinephrine Dose, Targeted Temperature Management, and Neurologic and Survival Outcomes Among Adults With Out‑of‑Hospital Cardiac Arrest. JAMA Netw Open. 2022;5:e2226191. https://doi.org/10.1001/jamanetworkopen.2022.26191.

33. Dankiewicz J, Cronberg T, Lilja G, Jakobsen JC, Levin H, Ullén S, et al. Hypothermia versus Normothermia after Out‑of‑Hospital Cardiac Arrest. N Engl J Med. 2021;384:2283-94. https://doi.org/10.1056/NEJMoa2100591.

34. Holgersson J, Meyer MAS, Dankiewicz J, Lilja G, Ullén S, Hassager C, et al. Hypothermic versus Normothermic Temperature Control after Cardiac Arrest. NEJM Evid. 2022;1. https://doi.org/10.1056/EVIDoa2200137.

35. Wolfrum S, Roedl K, Hanebutte A, Pfeifer R, Kurowski V, Riessen R, et al. Temperature Control After In‑Hospital Cardiac Arrest: A Randomized Clinical Trial. Circulation. 2022;146:1357- 66. https://doi.org/10.1161/CIRCULATIONAHA.122.060106.

36. Elbadawi A, Tan BE‑X, Assaf Y, Elzeneini M, Baig B, Hamed M, et al. Meta‑Analysis of Efficacy of Vasopressin During Cardiopulmonary Resuscitation. Am J Cardiol. 2022;181:122-9. https://doi.org/10.1016/j.amjcard.2022. 06. 042.

37. Holmberg MJ, Granfeldt A, Mentzelopoulos SD, Andersen LW. Vasopressin and glucocorticoids for in‑hospital cardiac arrest: A systematic review and meta‑analysis of individual participant data. Resuscitation. 2022;171:48-56. https://doi.org/10.1016/j.resuscitation. 2021. 12. 030.

38. Vallentin MF, Granfeldt A, Meilandt C, Povlsen AL, Sindberg B, Holmberg MJ, et al. Effect of calcium vs. placebo on long‑term outcomes in patients with out‑of‑hospital cardiac arrest. Resuscitation. 2022;179:21-4. https://doi.org/10.1016/j.resuscitation.2022. 07. 034.

39. Bougouin W, Slimani K, Renaudier M, Binois Y, Paul M, Dumas F, et al. Epinephrine versus norepinephrine in cardiac arrest patients with post‑resuscitation shock. Intensive Care Med. 2022;48:300-10. https://doi.org/10.1007/s00134-021-06608-7.

40. Kjaergaard J, Møller JE, Schmidt H, Grand J, Mølstrøm S, Borregaard B, et al. Blood‑Pressure Targets in Comatose Survivors of Cardiac Arrest. N Engl J Med. 2022;387:1456- 66. https://doi.org/10.1056/NEJMoa2208687.

41. Schmidt H, Kjaergaard J, Hassager C, Mølstrøm S, Grand J, Borregaard B, et al. Oxygen Targets in Comatose Survivors of Cardiac Arrest. N Engl J Med. 2022;387:1467-76. https:// doi.org/10.1056/NEJMoa2208686.

42. Ruijter BJ, Keijzer HM, Tjepkema‑Cloostermans MC, Blans MJ, Beishuizen A, Tromp SC, et al. Treating Rhythmic and Periodic EEG Patterns in Comatose Survivors of Cardiac Arrest. N Engl J Med. 2022;386:724-34. https://doi.org/10.1056/NEJMoa2115998.

43. Urbano V, Alvarez V, Schindler K, Rüegg S, Ben‑Hamouda N, Novy J, et al. Continuous versus routine EEG in patients after cardiac arrest. Resuscitation. 2022;176:68-73. https:// doi.org/10.1016/j.resuscitation.2022. 05. 017.

44. Sandroni C, D’Arrigo S, Cacciola S, Hoedemaekers CWE, Westhall E, Kamps MJA, et al. Prediction of good neurological outcome in comatose survivors of cardiac arrest: a systematic review. Intensive Care Med. 2022;48:389-413. https://doi.org/10.1007/s00134-022-06618-z.