Lethal Intoxication with Amphetamines

Czech version

Authors: P. Nohel; R. Kraus
Authors‘ workplace: ní klinika Fakultní nemocnice u sv. Anny v Brně, přednosta doc. MUDr. Pavel Ševčík, CSc. ; Anesteziologicko-resuscita&egrave
Published in: Anest. intenziv. Med., , 2001, č. 1, s. 47-48
Category:

Overview

Drug abuse becomes more common than ever before. Pervitin (methamphetamine) and other stimulants belong to the most abused „hard“ drugsin our country. Severe intoxication with amphetamine derivates may present as hyperpyrexia, rhabdomyolysis, acute renal insufficiency, coagulopathyand multiorgan failure. Dantrolene administration in those cases is discussed. Considering the pros and cons, early administration is probably advisableas a part of maximally intensive care for a young intoxicated patient. Early administration of antithrombin III should be a part of the DIC treatmentprotocol.

Key words:
intoxication - amphetamines - hyperthermia - dantrolene

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