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Nitric Oxide and Treatment of Respiratory Failure in Children


Authors: M. Filaun;  I. Lišková;  P. Pavlíček
Authors‘ workplace: KAR 2. LF a IPVZ ve FN Motol, resuscitační oddělení pro děti, přednosta doc. MUDr. K. Cvachovec, CSc.
Published in: Anest. intenziv. Med., , 2000, č. 4, s. 184-186
Category:

Overview

In years 1997 – 1998 there was treated in our PICU 521 children with mechanical ventilation, in 6 children failed conventional respiratory treatmentand led to increasing of hypoxemia with no response on treatment. Nitric oxide was in these cases used as a method for treatment of supposed pulmonaryhypertension. Indication for use of NO were SaO2 saturation below 85 %, paO2 below 10 kPa, hypoxemic index under 80, pulmonary shunts above40 % with application FiO2 1,0. Positive effect was minimum 10 % increased SaO2 saturation with improvement of other parameters as above. NOwas used in 6 children in age bracket 3 month to 14 years. Treatment continued from 4 to 27 days and used dose of NO was from 20 ppm to 35 ppm.Positive effect was in 5 cases, 1 patient died. Adverse effects of NO application were not noticed.

Key words:
nitric oxide – respiratory failure – children

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Labels
Anaesthesiology, Resuscitation and Inten Intensive Care Medicine
Topics Journals
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