Can fish oil improve wound healing in surgery?

Česká verze

Authors: Jana Neuwirthová; Břetislav Gál; Pavla Urbánková; Pavel Smilek
Authors place of work: Klinika otorinolaryngologie a chirurgie hlavy a krku LF MU a FN u sv. Anny v Brně
Published in the journal: Vnitř Lék 2016; 62(5): 406-412
Category: Přehledné referáty

Summary

A surgical insult induces both local and systemic inflammatory responses which, if inappropriate, could impair wound healing. According to many studies ω-3 polyunsaturated fatty acids from fish oil improve the process of wound healing by their immunomodulatory effect. In contrast to current anti-inflammatory drugs, which could alter immune defence and impair the resolution of inflammation, ω-3 fatty acids have a simultaneous anti-inflammatory pro-resolution effect which is not immunosuppressive. Besides that they improve cicatrix quality. With regard to this effect they prevent excessive or prolonged inflammation and wound complications.

Key words:
anti-inflammatory agent –⁠ cicatrix –⁠ fish oil –⁠ macrophage –⁠ ω-3 fatty acid –⁠ resolution of inflammation –⁠ Toll-like receptor –⁠ wound healing

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