Non-arrhythmic therapy of ventricular tachyarrhythmias and sudden cardiac death after acute myocardial infarction

English version

Autoři: P. Schweitzer
Působiště autorů: Division of Cardiology, Department of Medicine, Beth Israel Medical Center and Albert Einstein College of Medicine, New York, USA
Vyšlo v časopise: Vnitř Lék 2006; 52(12): 1185-1189
Kategorie: Přehledný referát

Prednesené na vedeckej pracovnej schôdzi Spolku lekárov v Košiciach dňa 25. apríla 2006 na XIII. memoriáli profesora F. Póra.

Souhrn

Ve vývoji managementu komorových tachyarytmií a prevenci náhlé srdeční smrti po akutním infarktu myokardu (AIM) došlo k významu posunu. Encainid a další antiarytmické léky použité v studii CAST byly nejenom neúčinné, ale zvyšovaly mortalitu po infarktu myokardu. Amiodaron měl některé pozitivní účinky na arytmické příhody, aniž by zvyšoval míru přežívání, a přínos ICD ke zlepšení výsledků krátce po AIM se neprokázal. Na druhé straně přínos beta-blokátorů, angiotenzin konvertujících inhibitorů a antagonistů aldosteronu z hlediska krátkodobého a dlouhodobého přežívání po AIM je prokázán. Referát pojednává o roli nearytmické terapie v prevenci komorové tachyarytmie a náhlé srdeční smrti po AIM.

Klíčová slova:
komorová tachyarytmie – náhlá srdeční smrt – akutní infarkt myokardu

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