Repetitive transcranial magnetic stimulation and chronic subjective tinnitus
Authors:
Jana Dvořáková 1; Martin Anders 1; Ivo Paclt 1; Jiří Raboch 1; Martin Holcát 2; Lucie Rathová 2; Berthold Langguth 3
Authors place of work:
Psychiatrická klinika 1. LF UK a VFN, Praha
1; Klinika otorhinolaryngologie 1. LF UK a VFN, Praha
2; Klinika pro psychiatrii, psychosomatiku a psychoterapii
Universität Regensburg, Německo
3
Published in the journal:
Cesk Slov Neurol N 2007; 70/103(4): 371-374
Category:
Přehledný referát
Summary
Chronic tinnitus is a frequent and often severely disabling disorder with a prevalence of over 8 % in subjects over 50 years. Tinnitus disrupts the full-value life of the patient and it is difficult to treat . The disorder is frequently associated with hearing loss and may be the result of neuroplastic alterations within the brain. Neuroimaging studies demonstrate increased activity within the central auditory system. TMS is a non-invasive method uses electromagnetic principles. TMS allows to modulate the excitability within superficial cortical areas. Stimulation effects can propagate also to functionally connected remote brain areas. It has been successfully employed in the treatment of other conditions associated with increased activity of the cerebral cortex. Applied as low frequency rTMS it has been proven to be effective for the treatment of disorders which are associated with focal hyperexcitability such as auditory hallucinations. There is a good theoretical basis and increasing research evidence suggesting a potential of TMS for the treatment of tinnitus. Further studies with large sample sizes and additional assessment of neurobiological effects are needed. Within this paper we discuss the potential for TMS as a therapy of tinnitus.
Key words:
chronic tinnitus – auditory cortex, hyperexcitability – repetitive transcranial magnetic stimulation – long-term depression – phantom auditory perception
Zdroje
1. Leske MC. Prevalence estimates of communicative disorder in the U.S. Language,hearing and vestibula disorders. ASHA 1981; 23(3): 229-237.
2. Chung DY, Gannon RP, Mason K. factors affecting the prevalence of tinnitus. Audiology 1984; 23(5): 441-452.
3. Noell CA, Meyerhoff WL. Tinnitus, diagnosis and treatment of this elusive symptom. Geriatrics 2003; 58(2): 28-34.
4. Moller AR. Pathophysiology of tinnitus. Otolaryngol Clin North Am 2003; 36: 249-266.
5. Muhlnickel W, Elbert T, Taub E, Flor H. Reorganization of auditory cortex in tinnitus. Proc natl Acad Sci U S A 1998; 95: 10340-10343.
6. Langguth B, Eichhammer P, Zowe M, Kleinjung T, Jacob P, Binder H et al. Altered motor cortex excitability in tinnitus patients: a hit at crossmodal plasticity. Neurosci Lett 2005; 380(3): 326-329.
7. Kaltenbach JA. Neurophysiologic mechanism of tinnitus. J Am Acad Audiol 2000; 11: 125-137.
8. Arnold W, Bertenstein P, Oestreicher E, Romer W, Schwaiger M. focal metabolic activation in the predominant left auditory cortex in patients suffering from tinnitus: a PET study with [18F]deoxyglucose. ORL J otorhinolaryngol Relat Spec 1996; 58: 159-199.
9. Lockwood AH, Salvi RJ, Coad ML, Towsley ML, Wack DS, Murphy BW. The functional neuroanatomy of tinnitus: evidence for limbic system links and neural plasticity. Neurology 1998; 50: 114-120.
10. Giraud AL, Chery-Croze S, Fischer G, Fischer C, Vighetto A, Gregoire MC et al. A selective imaging of tinnitus. Neuroreport 1999; 10: 1-5.
11. Mirz F, Gjedde A, Ishizu K, Pedersen CB. Cortical networks subserving the perception of tinnitus-PET study. Acta Otolaryngol Suppl 2000; 543: 241-243.
12. Dobie RA. A review of randomized clinical trials in tinnitus. Laryngoscope 1999; 109: 1202-1211.
13. Hoffman RE, Cavus I. Slow transcranial magnetic stimulation, long-term depotentiation, and brain hyperexcitability disorders. Am J Psychiatry 2002; 159: 1093-1102.
14. Eichhammer P, Langguth B, Marienhagen J, Kleinjung T, Hajak G. Neuronavigated repetitive transcranial magnetic stimulation in patients with tinnitus: a short case series. Biol Psychiatry 2003; 54: 862-865.
15. George MS, Belmaker RH. Transcranial magnetic stimulation in neuropsychiatry. Washington, DC: American Psychiatric Press 2000.
16. Chen R, Classen J, Gerloff C, Celnik P, Wassermann EM, Hallett M et al. Depression of motor cortex excitability by low-frequency transcranial magnetic stimulation. Neurology 1997; 48: 1398-1403.
17. Pascual-Leone A, Valls-Sole J, Wassermann EM, Hallett M. Responses to rapid-rate transcranial magnetic stimulation of the human motor cortex. Brain 1994; 117: 847-857.
18. Wang H, Wang X, Scheich H. LTD and LTP induced by transcranial magnetic stimulation in auditory cortex. Neuro Report 1996; 7: 521-525.
19. Pascual-Leone A, Bertres-Faz D, Keenan JP. Transcranial magnetic stimulation: studying the brain-behavior relationship by induction of “virtual lesion”. Philos trans R Soc Lond B Biol Sci 1999; 354: 1229-1238.
20. Skrdlantova L, Horacek J, Dockery C, Lukavsky J, Kopecek M, Preiss M. Novak T, Hoeschl C. The influence of low-frequency left prefrontal repetitive transcranial magnetic stimulation on memory for words but not for faces. Physiol Res 2005; 54: 123-128.
21. Loo CK, Mitchell PB, McFarquhar TF, Malhi GS, Sachdev PS. A sham-controlled trial of the efficacy and safety of twice-daily rTMS in major depression. Psychol Med 2007; 37: 341-349.
22. Plewnia C, Bartels M, Gerloff C. Transient suppression of tinnitus by transcranial magnetic stimulation. Ann Neurol 2003; 53: 263-266.
23. De Ridder D, Verstraeten E, van der Kelen K, De Mulder G, Sunaert S, Verlooy J et al. transcranial magnetic stimulation for tinnitus: influence of tinnitus duration on stimulation parameter choice and maximal tinnitus suppression. Otol Neurotol 2005; 26(4): 616-619.
24. De Ridder D, De Mulder G, Walsh V, Muggleton N, Sunaert S, Moller A. magnetic and electrical stimulation of the auditory cortex for intractable tinnitus. Case report. J Neurosurg 2004; 100(3): 560-564.
25. Kleinjung T, Eichhammer P, Langguth B, Jacob P, Marienhagen J, Hajak G et al. Long-term effects of repetitive transcranial magnetic stimulation (rTMS) in patients with chronic tinnitus. Otolaryngol Head Neck Surg 2005; 132(4): 556-69.
26. Langguth B, Eichhammer P, Wiegand R, Marienhagen J, Maenner P, Jacob P et al. Neuronavigated rTMS in a patient with chronic tinnitus. Effects of 4 week treatment. Neuroreport 2003; 14: 977-80.
27. May A, Hajak G, Gaenssbauer S, Langguth B, Kleinjung T, Eichhammer P. Structural brain alterations following 5 days of intervention: Dynamic aspects of neuroplasticity. Cerebral Cortex 2007; 17: 205-10.
Štítky
Dětská neurologie Neurochirurgie NeurologieČlánek vyšel v časopise
Česká a slovenská neurologie a neurochirurgie
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