Oral films as perspective dosage form

Česká verze

Authors: Veronika Walicová; Jan Gajdziok
Authors place of work: Veterinární a farmaceutická univerzita v Brně ; Ústav technologie léků, Farmaceutická fakulta
Published in the journal: Čes. slov. Farm., 2016; 65, 15-21
Category: Přehledy a odborná sdělení

Summary

Oral films, namely buccal mucoadhesive films and orodispersible films represent innovative formulations for administration of a wide range of drugs. Oral films show many advantageous properties and are intended for systemic drug delivery or for local treatment of the oral mucosa. In both cases, the film represents a thin layer, which could be intended to adhere to the oral mucosa by means of mucoadhesion; or to rapid dissolution and subsequent swallowing without the need of liquid intake, in the case of orodispersible films. Main constitutive excipients are film-forming polymers, which must in the case of mucoadhesive forms remain on the mucosa within the required time interval. Oral films are currently available on the pharmaceutical market and could compete with conventional oral dosage forms in the future.

Key words:
oral cavity • oral films • buccal mucoadhesive films • orodispersible films • film-forming polymers

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