Antimikrobiální, protiparazitické a protinádorové vlastnosti Hibiscus sabdariffa (L.) a jeho sloučeniny: in vitro a in vivo studie

English version

Autoři: Sherif T. S. Hassan; Katefiina Berchová; Miroslava Šudomová
Působiště autorů: Czech University of Life Sciences, Prague, Czech Republic ; Department of Applied Ecology, Faculty of Environmental Sciences
Vyšlo v časopise: Čes. slov. Farm., 2016; 65, 10-14
Kategorie: Přehledy a odborná sdělení

Souhrn

V posledních několika desetiletích si získal Hibiscus sabdariffa L. (Malvaceae, H. sabdariffa) velkou pozornost v oblasti výzkumu kvůli svému potenciálu biologické aktivity stejně jako pro svou velkou bezpečnost a snášenlivost. Po celá desetiletí zůstávají mikrobiální, parazitární a rakovinotvorná onemocnění vážnou hrozbou pro lidi a zvířata. K léčbě těchto chorob je velmi nutné naléhavě hledat nové zdroje – rostliny, které poskytují různé biologicky aktivní sloučeniny použitelné při léčbě některých onemocnění, protože v současné době většina léků používaných při léčbě má několik nežádoucí vedlejší účinků, toxicitu a rezistenci. V tomto článku se snažíme představit aktualizovaný přehled o in vitro a in vivo studiích, které ukazují významné léčebné vlastnosti surových extraktů a fytochemikálií – odvozené z H. sabdariffa jako antimikrobiální, protiparazitické a protinádorové látky. Možnosti využití a zkoumání H. sabdariffa vklinických studiích budou teprve diskutovány.

Klíčová slova:
Hibiscus sabdariffa L. • antimikrobiální látky • protinádorové látky • protiparazitické látky • přírodní látky

Zdroje

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