Sexual morbidity of cervical carcinoma survivors

Česká verze

Authors: P. Herboltová; A. Roztočil
Authors place of work: Gynekologicko-porodnické oddělení, KOC Nemocnice Jihlava, p. o., primář prof. MUDr. A. Roztočil, CSc.
Published in the journal: Ceska Gynekol 2016; 81(5): 349-354

Summary

Objective:
We are aware that patients with cervical carcinoma in the Czech Republic are poorly informed about sexual aspects of their therapy and there is also very poor attention paid to this problem in the Czech literature. Therefore we decided to evaluate the situation in a group of patients from our department using our own questionaire. We compared our results with contemporary world literature.

Design:
Questionnaire survey, comparison with world literature.

Setting:
Department of Gynecology and Obstetrics, Jihlava Hospital.

Methods:
Analysis of group of 25 patients with invasive cervical carcinoma, who had undergone radical hysterectomy, radiotherapy or both between 2009 and 2015. Patients were asked retrospectively using our own questionaire.

Conclusion:
Worldwide, the care of these patients is focusing also on their sexuality after therapy and various studies concentrate for several years on sexual morbidity in relation with performed therapeutic modality – radical hysterectomy or radiotherapy. Our group confirmed the worldwide results, mainly the lack of sexual interest and vaginal dryness, especially in women treated with radiotherapy. Also very poor knowledgeableness of the patients was confirmed.

Keywords:
cervical cancer, sexuality, morbidity, treatment, radical hysterectomy, radiotherapy

Zdroje

1. Bergmark, K., Avall-Lundqvist, E., Dickman, PW., et al. Vaginal changes and sexuality in women with a history of cervical cancer. N Engl J Med, 1999, 340, 18, p. 1383–1389.

2. Cibula, D., Petruželka, L., et al. Onkogynekologie. Praha: Grada Publishing, 2009, s. 295–307, 393–456.

3. Dušek, L., Mužík, J., Malúšková, D., Šnajdrová, L. Epidemiologie karcinomu hrdla děložního v mezinárodním srovnání. 2015. Dostupné z: http://www.cervix.cz/index.php?pg=pro-lekare--epidemiologie-karcinomu-hrdla-delozniho--mezinarodni-srovnani

4. Harding, Y., Ooyama, T., Nakamoto, T., et al. Radiotherapy- or radical surgery-induced female sexual morbidity in stages IB and II cervical cancer. Int J Gynecol Cancer, 2014, 24, 4, p. 800-805. doi: 10.1097/IGC.0000000000000112.

5. Jensen, PT., Groenvold, M., Klee, MC., et al. Early-stage cervical carcinoma, radical hysterectomy, and sexual function. A longitudinal study. Cancer, 2004, 100, 1, p. 97–106.

6. Jensen, PT., Groenvold, M., Klee, MC., et al. Longitudinal study of sexual function and vaginal changes after radiotherapy for cervical cancer. Int J Radiat Oncol Biol Phys, 2003, 56, 4, p. 937–949.

7. Lammerink, EA., de Bock, GH., Pras, E., et al. Sexual functioning of cervical cancer survivors: a review with a female perspective. Maturitas, 2012, 72, 4, p. 296–304. doi: 10.1016/j.maturitas.2012.05.006. Epub 2012 Jun 14. Review.

8. Mužík, J., Šnajdrová L., Gregor J. Epidemiologie karcinomu děložního hrdla v České republice. 2015. Dostupné z: http://www.cervix.cz/index.php?pg=pro-lekare--epidemiologie-karcinomu-hrdla-delozniho

9. Park, SY., Bae, DS., Nam, JH., et al. Quality of life and sexual problems in disease-free survivors of cervical cancer compared with the general population. Cancer, 2007, 110, 12, p. 2716–2725.

10. Pfaendler, KS., Wenzel, L., Mechanic, MB., Penner, KR. Cervical cancer survivorship: long-term quality of life and social support. Clin Ther, 2015, 37, 1, p. 39–48. doi: 10.1016/j.clinthera.2014.11.013.

11. Rai, B., Dhanireddy, B., Patel, FD., et al. Vaginal dose, toxicity and sexual outcomes in patients of cervical cancer undergoing image based brachytherapy. Asian Pac J Cancer Prev, 2014, 15, 8, p. 3619–3623.

12. Stankušová, H. Současná radioterapie a chemoterapie CA hrdla děložního. Databáze tuzemských onkologických konferenčních abstrakt, Konference 2010 XVII. Jihočeské onkologické dny, číslo abstraktu 009.

13. Vrzáčková, P., Sláma, J., Cibula, D., Weiss, P. Sexualita žen po prosté a radikální hysterektomii. Gynekolog, 2013, 4, s. 149–154.

14. Weiss, P., et al. Sexuologie. Praha: Grada Publishing, 2010, s. 217–224, 341–346, 401–405.

15. www.svod.cz

16. Ye, S., Yang, J., Cao, D., et al. A systematic review of quality of life and sexual function of patients with cervical cancer after treatment. Int J Gynecol Cancer, 2014, 24, 7, p. 1146–1157. doi: 10.1097/IGC.0000000000000207. Review.